Gonadotropin ‐releasing hormone agonists for ovarian protection during cancer chemotherapy: systematic review and meta‐analysis

ConclusionsLow quality evidence supports the use of GnRHa before and/or during chemotherapy to reduce the risk of POI and increase the probability of spontaneous pregnancy in the short term. Further high quality RCTs with more accurate assessment of ovarian reserve are needed to support any practical recommendation.

Source: Ultrasound in Obstetrics and Gynecology - October 21, 2017 Category: Radiology Authors: Janaina C. Senra, Matheus Roque, Mariza C. T. Talim, Fernando M. Reis, Rubens L. C. Tavares Tags: Systematic Review Source Type: research