Cryotherapy May Prevent Chemo - Induced Neuropathy
Breast cancer patients on paclitaxel had lower incidence of peripheral neuropathy with cryotherapy
ConclusionsStrategies to prevent painful peripheral neuropathy are urgently needed. In this current trial, dropout due to discomfort precluded adequate power to fully understand the potential benefits of cryotherapy. Much more research is needed to discover safe and effective preventive strategies that can be easily implemented within busy infusion centers.
Condition: Breast Cancer Interventions: Device: Elasto-Gel™; Drug: Paclitaxel Sponsors: National Cancer Centre, Singapore; Terry Fox Foundation; Duke-NUS Academic Medicine Research Institute; Singapore General Hospital Recruiting
Cryotherapy delivered to the hands and feet during weekly paclitaxel chemotherapy significantly reduces the incidence of peripheral neuropathy in patients with breast cancer.Medscape Medical News
Conditions: Chemotherapeutic Agent Toxicity; Pain; Peripheral Neuropathy; Recurrent Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer; Therapy-related ToxicityInterventions: Procedure: cryotherapy; Other: questionnaire administration; Pr...