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EQ-5D-5L Utility Values For Spanish Patients With Painful Chronic Osteoarthritis, Low-Back-Pain Or Cancer Pain

The objective was to fit equations allowing to estimate the age and sex adjusted utility value of the EQ-5D-5L according with the severity of pain for patients with PCOA, CLBP or CP in Spain.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research

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This article reviews the clinical questions and bottom-line answers from these studies. Blood pressure should be measured after a period of rest, using a bare arm, and orthostatic blood pressure is more predictive when measured after one minute of standing rather than three minutes. Intensive blood pressure lowering results in cardiovascular benefits but also renal harms in high-risk patients with an average age of 68 years. The initiation of a statin for primary prevention does not reduce cardiovascular events in adults 65 years or older. Sterile gloves do not reduce the risk of infection for common outpatient skin proced...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Listen to L Susan Wieland of the  Cochrane Complementary Medicine Field talk toDr. Mark Porter on Inside Health about Cochrane evidence on Yoga (start at 23 minutes). Yoga originated thousands of years ago in India as an integrated physical, mental, and spiritual practice based on ancient Vedic philosophy, and is connected to Ayurveda, the system of traditional Indian medicine. During the 20th century, yoga became increasingly recognised outside India, and over the past decades it has continued to grow in popularity worldwide as system for promoting health and well-being. While modern yoga often focuses on physic...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
Opioid prescribing has markedly increased in UK and worldwide, predominantly for chronic non-cancer pain (CNCP). CNCP includes conditions such as fibromyalgia, low back pain and osteoarthritis (OA). Evidence suggests that widespread use of opioids in CNCP is associated with risks of diversion and abuse, overdose and death. However, opioid prescribing data in specific medical conditions are limited and no study has examined the trends of prescribing in patients with OA in UK. OA affects around 7 million people in the UK with knee joint being most commonly affected.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research
This article provides an updated review on the analgesic efficacy and safety of anti-NGF agents based on data from fully published studies and public information from websites, and discusses the possible future role of these agents in managing chronic pain. The efficacy of anti-NGF mAbs was highly variable depending on the chronic pain condition studied. The most consistent and convincing results were obtained in patients with symptomatic osteoarthritis of the knee and/or hip. Conversely, studies in non-specific lower back pain and peripheral neuropathic pain generated mixed results. Finally, there was no conclusive eviden...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
It seems odd to me that there’s much argument about central sensitisation in pain circles. I thought the idea of central sensitisation was well-established based on research from some years ago – but apparently there are still arguments about its relevance, and lots of debate about how to identify it clinically. This post is based mainly on a presentation by Jo Nijs from Pain in Motion, at the recent NZ Pain Society meeting in Nelson. In this post I want to briefly review the material presented by Jo suggesting that central sensitisation is a thing. I’ll write more about assessment in a future blog, or th...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: Chronic pain Clinical reasoning Pain conditions Research Science in practice biopsychosocial Health Source Type: blogs
Over the last year, the general public has been inundated with a steady stream of reports about the dangers of opiates — pain medicines like codeine, Percocet, and OxyContin. The harm in terms of ruined lives and death from illicit drugs such as heroin is not news. But what is new, and concerning, are the risks of prescription pain medicines — those doctors prescribe for pain due to a range of causes, including musculoskeletal problems like low back pain. The history of using opiates for chronic pain Back pain isn’t a new problem either, but the history of how doctors have treated it is probably new to ma...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Addiction Back Pain Behavioral Health Pain Management Source Type: news
ConclusionDespite initial reports, tanezumab treatment was not associated with an increase in ON but was associated with an increase in RPOA. Higher doses of tanezumab, tanezumab administered with nonsteroidal antiinflammatory drugs, and preexisting subchondral insufficiency fractures were risk factors for RPOA in this cohort.
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Osteoarthritis Source Type: research
Conclusions: Despite initial reports, tanezumab treatment was not associated with an increase in ON, but was associated with an increase in RPOA. Higher doses of tanezumab, tanezumab administered with NSAIDs, and preexisting subchondral insufficiency fractures were risk factors for RPOA in this cohort. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Full Length Source Type: research
The FDA today released its list of the pre-market approvals it granted for medical devices in May 2015: Summary of PMA Originals &Supplements Approved Originals: 5 Supplements: 51 Summary of PMA Originals Under Review Total Under Review: 55 Total Active: 26 Total On Hold: 29 Summary of PMA Supplements Under Review Total Under Review: 547 Total Active: 379 Total On Hold: 168 Summary of All PMA Submissions Originals: 1 Supplements: 62 Summary of PMA Supplement PMA Approval/Denial Decision Times Number of Approvals: 51 Number of Denials: 0 Average Days Fr Receipt to Decision (Total Time): 109.5 FDA Time: 86....
Source: Mass Device - Category: Medical Equipment Authors: Tags: Food & Drug Administration (FDA) Regulatory/Compliance Source Type: news
View the Podcast here. Chronic pain affects nearly 90 million Americans. It usually begins with a sports injury, car accident or health condition like migraines, diabetes, arthritis and cancer.  Chronic pain is different from the acute pain of stubbing your toe and often feels like burning, shooting, or shocking sensations.  The good news is that today’s pain specialists have sophisticated new treatments — from medications to advanced technologies — to provide chronic pain relief.    Chronic pain can be classified as nociceptive or neuropathic pain.  In some cases (nociceptive pa...
Source: Dr. Donna, MedicineWoman - Category: Medical Scientists Authors: Tags: Cancer Integrative medicine Personal Health accupuncture arthritis diabetic neuropathy management massage migraine pain PENS treatment Source Type: blogs
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