Cost-Effectiveness Of A Potential Combined Vaccine Against Lyme Borreliosis And Tick-Borne Encephalitis In Slovenia

To assess cost-effectiveness of a vaccine that would protect against both Lyme Borreliosis (LB) and tick-borne encephalitis (TBE) in a highly endemic setting in Slovenia.
Source: Value in Health - Category: International Medicine & Public Health Authors: Source Type: research

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Authors: Figoni J, Chirouze C, Hansmann Y, Lemogne C, Hentgen V, Saunier A, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Caumes E, Eldin C, de Broucker T, Jaulhac B, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Gocko X, Dieudonné M, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Lenormand C, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, endorsed by scientific societies Abstract Lyme borreliosis is transmitted en France by the tick Ixodes ricinus, endemic in metropolitan France. In the absence of vaccine licensed for use in humans, primary prevent...
Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
a Szturcová Daniel Růžek Kurt Pfister Libor Grubhoffer In Europe, Lyme borreliosis (LB) and tick-borne encephalitis (TBE) are the two vector-borne diseases with the largest impact on human health. Based on data on the density of host-seeking Ixodes ricinus ticks and pathogen prevalence and using a variety of environmental data, we have created an acarological risk model for a region where both diseases are endemic (Czech Republic—South Bohemia and Germany—Lower Bavaria, Upper Palatinate). The data on tick density were acquired by flagging 50 sampling sites three times in a single seas...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Purpose: The South Bohemian Region of the Czech Republic is an endemic area of tick-borne encephalitis (TBE). In 2017, the inhabitants of Římov municipality developed a serious course of TBE and Lyme borreliosis (LB). This led experts to research and serology examinations of the inhabitants of Římov in order to detect the seroprevalence of TBE and LB.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: 21.130 Source Type: research
This study assessed cost-effectiveness of a potential anti-tick vaccine that would protect against both Lyme borreliosis (LB) and tick-borne encephalitis (TBE) in a highly endemic setting of Slovenia.A Markov model was developed to estimate cost-effectiveness of a vaccine with potential combined protection against LB and TBE from the societal perspective. The model expressed time in annual cycles, followed a target population through their lifetime, and applied an annual discounting of 3%. A target population entered the model in a susceptible state, with time dependent probabilities to acquire LB/TBE. Disease manifestatio...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
A constant increase in the incidence of tick-borne diseases has been observed in Europe since the last decade of the twentieth century. In Poland, the most common zoonoses transmitted by Ixodes ricinus ticks are tick-borne encephalitis (TBE) and Lyme disease. These diseases have become a serious clinical problem, especially in Podlaskie Region, which is considered an endemic area for these diseases (Czupryna et al., 2011).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Publication date: Available online 6 July 2017 Source:Ticks and Tick-borne Diseases Author(s): Viktor Zöldi, Topi Turunen, Outi Lyytikäinen, Jussi Sane Tick-borne encephalitis (TBE) and Lyme borreliosis (LB) are endemic in Finland, with tens and thousands of cases, respectively, reported annually. We performed a field survey to investigate people’s knowledge, attitudes and practices (KAP) regarding ticks, tick-borne diseases, and prevention strategies. The KAP were assessed using a pre-validated anonymous questionnaire consisting of 39 questions and statements. On two consecutive days in July 2016, conveni...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Abstract Tick-borne encephalitis (TBE) is an arbovirus induced by tick-borne encephalitis virus (TBEV) transmitted by tick bite. The disease is rare in France (two to three cases per year) but endemic zones extend from Western Europe to the east coast of Asia (10,000-15,000 cases per year). An 8-year-old boy was admitted to our pediatric ward in Strasbourg (France) for febrile headache with diplopia. Four days after a tick bite, he declared a febrile headache together with maculopapular rash on the elbows, knees, and cheeks. Fourteen days after the outbreak of symptoms, he showed confusion, drowsiness, and binocul...
Source: Archives de Pediatrie - Category: Pediatrics Authors: Tags: Arch Pediatr Source Type: research
Publication date: Available online 24 October 2015 Source:Ticks and Tick-borne Diseases Author(s): Jani J. Sormunen, Tero Klemola, Eero J. Vesterinen, Ilppo Vuorinen, Jukka Hytönen, Jari Hänninen, Kai Ruohomäki, Ilari E. Sääksjärvi, Elina Tonteri, Ritva Penttinen Studies have revealed that Ixodes ricinus (Acari: Ixodidae) have become more abundant and their geographical distribution extended northwards in some Nordic countries during the past few decades. However, ecological data of tick populations in Finland are sparse. In the current study, I. ricinus abundance, seasonal questin...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 27 April 2015 Source:Ticks and Tick-borne Diseases Author(s): V. Hönig , P. Svec , P. Halas , Z. Vavruskova , H. Tykalova , P. Kilian , V. Vetiskova , V. Dornakova , J. Sterbova , Z. Simonova , J. Erhart , J. Sterba , M. Golovchenko , N. Rudenko , L. Grubhoffer Spatial distribution of Ixodes ricinus tick host-seeking activity, as well as prevalence of Borrelia burgdorferi sensu lato and tick-borne encephalitis virus (TBEV) were studied in the TBE endemic area of South Bohemia (Czech Republic). High variability in tick abundance detected in a network of 30 study sites was most close...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Conclusion Overall, this review provides insights into how climate change might lead to the transmission of tropical diseases in what are currently temperate parts of the world, such as the UK. Predicting what may happen in the future can help countries make sure they are prepared for such an eventuality. This review was informed by a search for relevant literature, but may not have captured or included all relevant studies. Most of the studies were modelling studies, which are reliant on various assumptions that may or may not turn out to be correct. It's not possible to say with any certainty what will occur in the fut...
Source: NHS News Feed - Category: Consumer Health News Tags: Medical practice QA articles Source Type: news
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