Collagenous matrix supported by a 3D-printed scaffold for osteogenic differentiation of dental pulp cells

Spontaneous regeneration capacity of bone tissue is only limited to small defects. Large bone defects as consequence of trauma, osteoporotic fracture, tumors, and congenital deformity require surgical intervention [1]. Allografts and autografts are the main clinical strategies to fill bone cavities. However, autografts are restricted by site morbidity and approachability of the transplantable bone. Also, allografts increase the risk of immune-rejection reactions and infectious diseases transmission [2].

Source: Dental Materials - October 17, 2017 Category: Materials Science Authors: Farahnaz Fahimipour, Erfan Dashtimoghadam, Morteza Rasoulianboroujeni, Mostafa Yazdimamaghani, Kimia Khoshroo, Mohammadreza Tahriri, Amir Yadegari, Jose A. Gonzalez, Daryoosh Vashaee, Douglas C. Lobner, Tahereh S. Jafarzadeh Kashi, Lobat Tayebi Source Type: research