Label-free brainwide visualization of senile plaque using cryo-micro-optical sectioning tomography

Optical visualization of pathological changes in Alzheimer ’ s disease (AD) can facilitate exploration of disease mechanisms and treatments. However, existing optical imaging methods have limitations on mapping pathological evolution in the whole mouse brain. Previous research indicated ...

Source: Optics Letters - October 17, 2017 Category: Physics Authors: Yilin Luo Anle Wang Mengmeng Liu Tian Lei Xiaochuan Zhang Zhaobing Gao Hualiang Jiang Hui Gong Jing Yuan Source Type: research