BDNF Val66Met polymorphism, Life Stress and Depression: a Meta-analysis of Gene-Environment Interaction

Depression is thought to be multifactorial in etiology, including genetic and environmental components. While a number of gene-environment interaction studies have been carried out, meta-analyses are scarce. The present meta-analysis aimed to quantify evidence on the interaction between brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and stress in depression.

Source: Journal of Affective Disorders - October 16, 2017 Category: Neurology Authors: Mingzhe Zhao, Lu Chen, Jiarun Yang, Dong Han, Deyu Fang, Xiaohui Qiu, Xiuxian Yang, Zhengxue Qiao, Jingsong Ma, Lin Wang, Shixiang Jiang, Xuejia Song, Jiawei Zhou, Jian Zhang, Mingqi Chen, Dong Qi, Yanjie Yang, Hui Pan Tags: Review article Source Type: research