Electroacupuncture alleviates chemotherapy ‐induced pain through inhibiting phosphorylation of spinal CaMKII in rats

ConclusionsElectroacupuncture activates 5‐HT 1A receptors in the spinal cord and inhibits p‐CaMKII to alleviate both allodynia and hyperalgesia. The data support acupuncture/EA as a complementary therapy for CIP.
SignificanceElectroacupuncture (EA) activates spinal 5‐HT1A receptors to inhibit p‐CaMKII to alleviate paclitaxel‐induced pain. Acupuncture/EA may be used as a complementary therapy for CIP.

Source: European Journal of Pain - October 16, 2017 Category: Anesthesiology Authors: Y. Zhang, A. Li, J. Xin, K. Ren, B.M. Berman, L. Lao, R. ‐X. Zhang Tags: Original Article Source Type: research