Single-unit activity of the anterior globus pallidus internus in Tourette patients and posterior globus pallidus internus in Dystonic patients

Dystonia is a movement disorder characterised by involuntary sustained muscle contractions that lead to twisting, repetitive movements and abnormal postures. Two types of Dystonia can be distinguished: Primary Dystonia has no evidence of other pathological abnormalities, and secondary Dystonia which is associated with neurological lesions, either degenerative or traumatic (Albanese et al. 2013). Tourette ’s Syndrome (TS) is a neuropsychiatric disorder that is chronic and typically characterised by motor and vocal tics.

Source: Clinical Neurophysiology - October 14, 2017 Category: Neuroscience Authors: Andrea Giorni, Fran çois Windels, Peter G. Stratton, Raymond Cook, Paul Silberstein, Terrence Coyne, Peter A. Silburn, Pankaj Sah Source Type: research