Candida albicans possess a highly versatile and dynamic high ‐affinity iron transport system important for its commensal‐pathogenic lifestyle

This article is protected by copyright. All rights reserved. All organisms must strike a delicate balance between acquiring the essential nutrient iron and avoiding its toxicity. We demonstrate that the human fungal pathogen Candida albicans has evolved a sophisticated, robust iron acquisition system that can assemble different sets of high‐affinity iron transporters according to iron availability. This trait especially suits the commensal‐pathogenic lifestyle of C. albicans that traverses host niches with drastically different levels of iron supply.
Source: Molecular Microbiology - Category: Microbiology Authors: Tags: Research Article Source Type: research