NHC-catalyzed regiodivergent syntheses of difunctionalized 3-pyrazolidinones from [small alpha]-bromoenal and monosubstituted hydrazine

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02041D, PaperChenxia Yu, Shide Shen, Ligen Jiang, Jing Li, Yumiao Lu, Tuanjie Li, Changsheng Yao A formal [3+2] annulation of [small alpha]-bromoenal with monosubstituted hydrazine could give 1,5 or 2,5-difunctionalized 3-pyrazolidinone regiodivergently by tuning the structure of N-Heterocyclic Carbene (NHC) catalyst. The moderate to high yields,... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 13, 2017 Category: Molecular Biology Authors: Chenxia Yu Source Type: research