Spearheading Advancements in Surgical Sealants
Surgeons and clinicians have used surgical sealants for closing or reconnecting ruptured tissues, or as an adjunct to sutures and staples, for years. However, advancements in technology have led general surgeons and specialists to consider sealants for a wider range of applications and with increased frequency. Increasing Ease of Use Surgical sealants aren't as easy to use as a tube of Crazy Glue. Surgeons must mix and use some agents precisely and promptly to be effective. Delivery systems vary from a syringe, proprietary applicator, or through an endoscope. Most require special training. Sylys®, an elastic, resorbable, synthetic sealant developed by Cohera Medical, requires no mixing. The single-part sealant uses a chemistry that produces rapid curing initiated by contact with tissue moisture. Its custom applicator allows surgeons to use the product in either open or laparoscopic procedures. "We wanted doctors to be doctors, not engineers," said Cohera president and CEO Patrick Daly. "We wanted to create a great product that's easy to use and straightforward to apply." Cohera designed Sylys to help reduce anastomotic leakage in gastrointestinal surgical procedures. Used in conjunction with sutures or staples, Sylys supports anastomosis during the first few days post-surgery—a time when patients run the highest risk of bowel leakage. Daly said the sealant, in preclinical studies, reduced leakage by nearly 60 percent. "A bowel leak...
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