Factor VII-activating protease: sex-related association with coronary artery calcification
Factor VII-activating protease (FSAP) may regulate development of cardiovascular disease (CVD). We evaluated sex differences in FSAP measures and examined the association between FSAP and coronary artery calcification (CAC) in a middle-aged population. Participants were randomly selected citizens aged 50 or 60 without CVD, diabetes mellitus, Marburg I polymorphism, or hormone replacement therapy (HRT). FSAP protein concentration (total FSAP), FSAP urokinase-activating capacity (FSAP GP), and FSAP GP/total FSAP (specific FSAP activity) were measured. Cardiac computed tomography (CT) determined the Agatston score, dividing the study population in three groups: (1) Agatston score = 0 U, (2) Agatston score = 1–99 U, or (3) Agatston score more than 99 U. A total of 134 women and 116 men were included. Total FSAP, FSAP GP, and specific FSAP activity were independently higher in women (97.4%, 81.1%, 0.84, respectively) compared with men (87.5%, 68.7%, 0.79, respectively) (P
CONCLUSION:: To conclude, the outcomes of radiocephalic arteriovenous fistulas created by nephrologists are at par with historic outcomes. PMID: 30784345 [PubMed - as supplied by publisher]
The effect of meal on blood glucose concentration is a key issue in diabetes mellitus because its estimation could be very useful in therapy decisions. In the case of type 1 diabetes mellitus (T1DM), the therapy based on automatic insulin delivery requires a closed-loop control system to maintain euglycaemia even in the postprandial state. Thus, the mathematical modelling of glucose metabolism is relevant to predict the metabolic state of a patient. Moreover, the eating habits are characteristic of each person, so it is of interest that the mathematical models of meal intake allow to personalise the glycaemic state of the ...
DIABETES type 2 risk could be lowered by making some diet or lifestyle changes. You could prevent high blood sugar symptoms and signs by making these small changes to your usual Chinese or Indian takeaway order.
An MIT-led research team has developed a drug capsule -- about the size of a blueberry -- that could be used to deliver oral doses of insulin, potentially replacing the injections that people with Type 1 diabetes have to give themselves every day. In tests in animals, the researchers showed that ...This is an NSF Multimedia Gallery item.
Ruifeng Shi, Yanping Wang, Xiaofei An, Jianhua Ma, Tongzhi Wu, Xiaojin Yu, Su Liu, Liji Huang, Lijuan Wang, Jingshun Liu, Jing Ge, Shanhu Qiu, Han Yin, Xiaolai Wang, Yao Wang, Bingquan Yang, Jiangyi Yu, Zilin Sun
CONCLUSIONS: The results for diabetic foot prevention knowledge and practices are not very encouraging. In light of this situation, primary care programs are important, where nurses provide effective education, as a mechanism for modifying the behavior of people with diabetes mellitus. PMID: 30785550 [PubMed - in process]
CONCLUSIONS: Most participants reported having healthy life habits, which they believe influence on disease control. Among the investigated parameters, only the habit of not smoking was associated with the absence of hypertensive peaks; the other habits did not present statistical association with the comorbidities. PMID: 30785546 [PubMed - in process]
CONCLUSION: The results show that there is a delay in wound healing in diabetic patients. PMID: 30785542 [PubMed - in process]
CONCLUSIONS The MI-SNP and MII-SNP FSAP gene polymorphisms were not predictive or prognostic biomarkers for CAD or its main risk factors. However, the presence of the MII-SNP polymorphism was associated with a reduced risk of developing CAD. PMID: 29927903 [PubMed - in process]