Visible-light-mediated direct difluoromethylation of alkynoates: Synthesis of 3-difluoromethylated coumarins

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02366A, CommunicationMei Zhu, Weijun Fu, Zhiqiang Wang, Chen Xu, Baoming Ji A photoredox-catalyzed direct difluoromethylation of alkynoates has been developed. The well-designed photoredox system induces a single-step, regioselective installation of a CF2H onto alkynes. Difluoromethyl sulfone was used as an easy... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research