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Light Therapy May Help Some With Bipolar Disorder

Study found an hour in front of a light box helped ease depressive symptoms
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Condition:   Bipolar Depression Intervention:   Device: Light Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
This study found that once-daily treatment with valbenazine at 80 mg/day significantly improved the symptoms of tardive dyskinesia compared with placebo in a population of patients with schizophrenia, schizoaffective disorder, or a mood disorder. The med ication was generally well tolerated, even among patients taking concomitant antipsychotics, and the psychiatric status of the patients remained stable throughout the trial.In addition to the article by Sit and colleagues referenced above, the following studies were selected by BBRF in its list of the top advancements and breakthroughs by Foundation grantees in 2017 (in ch...
Source: Psychiatr News - Category: Psychiatry Tags: American Journal of Psychiatry bipolar depression bipolar disorder Brain and Behavior Research Foundation ketamine NEJM Journal Watch Psychiatry rapastinel tardive dyskinesia Source Type: research
Light therapy (LT) is efficacious for bipolar depression with effect sizes equivalent to those in antidepressant pharmacotherapy trials. Patients with bipolar disorder (BD) show a 15 –40% rate of manic switches during antidepressant drug treatment. The rate of manic switches during LT has never been estimated.We searched all the literature studies reporting effects of antidepressant LT in BD. 41 studies described 799 patients with BD treated with antidepressant LT, from among which 7 (0.9%) switched into mania and 11 (1.4%) switched into hypomania.
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Patients with bipolar depression who are not responding to pharmacotherapy may benefit from add-on transcranial direct current stimulation (tDCS), according to astudy inJAMA Psychiatry. tDCS is a low-cost, noninvasive technique that applies weak, direct currents into the brain via electrodes placed over the scalp.In this small study, patients with bipolar depression who received active tDCS showed superior improvement after six weeks of treatment compared with those who received sham treatment. Additionally, active tDCS did not induce more manic/hypomanic episodes —which the authors noted is a significant concern whe...
Source: Psychiatr News - Category: Psychiatry Tags: bipolar depression bipolar disorder dorsolateral prefrontal cortex Hamilton Depression Rating Scale JAMA Psychiatry tDCS Transcranial Direct Current Stimulation Source Type: research
The combination of three cycles of sleep deprivation (SD), light therapy (LT), and lithium has recently been proposed as a possible first-line treatment for bipolar depression. However, it is unclear whether early improvement predicts final response/remission in bipolar depression treated with this regimen.
Source: Journal of Affective Disorders - Category: Neurology Authors: Tags: Research paper Source Type: research
For 30 years, bright light therapy (BLT) has been considered as an effective, well-tolerated treatment for seasonal affective disorder (SAD). Because of low response rates, new treatment strategies are needed for bipolar depression (BD), which resembles SAD in certain respects. Few placebo-controlled studies of BLT efficacy have been carried out for BD. Accordingly, this study evaluates the efficacy and safety of BLT as an add-on treatment for BD. Thirty-two BD outpatients were randomly assigned to BLT (10000 lx) or dim light (DL,
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Source: NPR Health and Science - Category: Consumer Health News Authors: Source Type: news
Conclusions rs7713917 influenced brain grey and white matter structure and function in BD, long term effects of lithium on white matter structure, and antidepressant response to chronotherapeutics, thus suggesting that glutamatergic neuroplasticity and Homer 1 function might play a role in BD psychopathology and response to treatment.
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
It’s that time of year again when the highly sensitive types among us who thrive with lots of sunlight begin to wither with the plants as the sun begins to hide. Not only do we get less vitamin D (and deficiencies have been linked to depression), but the change in sunlight affects our circadian rhythm — the body’s internal biological clock that governs certain brain activity and hormone production. In some people, the change of mood-related chemicals can cause seasonal affective disorder (SAD), also known as winter blues or seasonal depression. For an episode of major depression to be class...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Alternative and Nutritional Supplements Bipolar Depression Holiday Coping Mental Health and Wellness Roundup Self-Help Light therapy Sad Sadness Seasonal Affective Disorder Seasonal Depression seasonal depressive disorder Vitamin Source Type: blogs
By Christian Jarrett The clocks have gone back and there’s a chill in the air. It’s well known that during these darker months, a significant minority of us experience unwelcome negative changes to our mood (at least if you believe in the notion of Seasonal Affective Disorder or SAD, which not all experts do). Now an intriguing study in Psychiatry Research has explored the link this condition may have with another psychiatric diagnosis, Obsessive Compulsive Disorder (OCD). The results suggest that people with OCD are more likely than average to experience seasonal effects on their mood, and that for these ...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Mental health Source Type: blogs
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