Two WNY hospitals to share doc notes with patients
Ever leave the doctor and second guess the information you sort of remember? Two Western New York hospitals are implementing a new system designed to give patients access to the notes written by their health care providers. Niagara Falls Memorial Health System and Roswell Park Cancer Institute are among seven hospitals statewide to receive grant funding of about $125,0 00 apiece from the New York State Health Foundation to add the OpenNotes system. Niagara Falls Memorial will implement the system…
Markus Schosserer, Johannes Grillari, Michael Breitenbach
Alan Dal Pra, Thomas Zilli, Stephane Supiot
This article is protected by copyright. All rights reserved.
Adebola Giwa, Rizwan Ahmed, Thomas Donner, Hideo Yagita, Abdel Rahim A. Hamad
This amount cuts the risk of heart disease by 15% and early death by 17%, found the University of Southampton. It also slashes chances of certain cancers, diabetes, liver disease and dementia.
Conclusions: miR-27a, miR-27b, miR-9, miR10a and miR-10b were up-regulated in PDAC cells compared to HPDE cells. The up-regulation of these miRNAs was not responsible for the down-regulation of RAR α, RARβ, RXRα and RXRβ in PDAC cells.Cell Physiol Biochem 2017;44:644 –656
Conclusion: Our results support the hypothesis that CAV-1 knockdown by siRNA causes increased radiosensitivity in basal-like TNBC cells. The mechanisms associated with this effect are reduced DNA repair through delayed CAV-1-associated EGFR nuclear accumulation and induction ofG2/M arrest and apoptosis through the combined effects of CAV-1 siRNA and radiation.Cell Physiol Biochem 2017;44:778 –791
Conclusion: Taken together, melatonin has different antioxidative effects on tumour cells compared to non-tumour ones; it also differs in the ability to induce apoptosis through the type 1 sodium/calcium exchanger, and type 1 IP3 receptor. Different targeting of calcium transport systems in tumour and normal, non-tumour cells is suggested as a key mechanism how melatonin can exert its anticancer effects. Therefore, it might have a potential as a novel therapeutic implication in cancer treatment.Cell Physiol Biochem 2017;44:763 –777