Updates on cardiovascular outcome trials in diabetes
In 2008 the Food and Drug Administration introduced a guidance for industry that requires the investigation of cardiovascular outcomes of glucose-lowering medications. Since then, an increasing number of cardi...
TYPE 2 DIABETES symptoms include passing more urine than usual and feeling tired all the time. If the condition is left untreated, a number of other health problems can follow, so it ’s important to recognise all the signs - including feeling very thirsty.
This NIHR Signal finds that for western high-income countries such as the UK, an estimated 15% to 16% of cancers could be avoided by preventing diabetes, obesity or excess weight. Although the links between high BMI, diabetes and cancer have been known for some time, this study presents the first calculations of attributable risk for 175 countries. This represents the proportion of cancers that could be prevented if the risk factors were eliminated.
Diabetic patients are more prone to the development of foot ulcers, because their underlying tissues are exposed to colonization by various pathogenic organisms. Hence, biofilm formation plays a vital role in disease progression by antibiotic resistance to the pathogen found in foot infections. The present study has demonstrated the correlation of biofilm assay with the clinical characteristics of diabetic foot infection. The clinical characteristics such as the ulcer duration, size, nature, and grade were associated with biofilm production.
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Yi-Guang Chen, Clayton E. Mathews, John P. Driver
This article provides insight into the clinical manifestations of CDC73-related disorders and discusses ways to improve case detection in primary hyperparathyroidism.Journal of Clinical Endocrinology &Metabolism
Find out how muscle function and exercise performance are impacted among patients receiving statin treatment.Journal of Clinical Endocrinology &Metabolism
New J. Chem., 2018, Advance Article DOI: 10.1039/C7NJ04678B, PaperS. Ferreira, A. Leite, T. Moniz, M. Andrade, L. Amaral, B. de Castro, M. Rangel EPR/51V-NMR parallel studies of [VO(3,4-HPO)2] complexes in MOPS buffer and POPC liposome suspensions provide information regarding solvents for oral administration. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Authors: Zhang X, Chee WK, Liu S, Tavintharan S, Sum CF, Lim SC, Kumari N Abstract Purpose: Osteopontin (OPN) is a proinflammatory cytokine with diverse functions. Increased levels of OPN in vitreous fluid have been reported in patients with diabetic retinopathy (DR); however, studies on circulating OPN levels in DR are limited. We aim to examine the association of plasma OPN levels with the presence and severity of DR in a multiethnic cohort with type 2 diabetes mellitus (type 2 diabetes) in Singapore. Methods: Plasma levels of OPN were measured using enzyme-linked immunosorbent assay. Digital color fundus pho...
This article summarizes the milestones in the development of ertugliflozin leading to its first approval for T2DM.