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Acinetobacter baumannii Virulence Traits: A Comparative Study of a Novel Sequence Type with Other Italian Endemic International Clones

Cecilia Ambrosi, Daniela Scribano, Marta Aleandri, Carlo Zagaglia, Laura Di Francesco, Lorenza Putignani, Anna Teresa Palamara
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research

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ConclusionsCarbapenem-nonsusceptibleA. baumannii-calcoaceticus complex are endemic in this setting. Prevention requires source control and limiting transmission of strains.Trial registrationThe study was retrospectively registered atwww.trialregister.nl (No:5541). Candidate number: 23,527, NTR number: NTR5541, Date registered NTR: 22nd December 2015.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Conclusions These results indicate that the surveillance program implemented was effective in preventing the spread of multidrug-resistant organisms in the hospital.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Publication date: Available online 19 September 2017 Source:Medicina Intensiva (English Edition) Author(s): D. Escudero, L. Cofiño, L. Forcelledo, B. Quindós, C. Calleja, L. Martín
Source: Medicina Intensiva - Category: Intensive Care Source Type: research
AbstractWe evaluated an infection control (IC) program influenced by personnel and material resource shortages on the incidence of bloodstream infections (BSI) due to carbapenem-resistantKlebsiella pneumoniae (CRKP),Acinetobacter baumannii (CRAB), andPseudomonas aeruginosa (CRPA) in an endemic region. Between January 2010 and December 2015, all BSI episodes caused by CRKP, CRAB, and CRPA were recorded. An IC bundle was implemented in January 2012. We evaluated the effect of the interventions on BSI rates between the pre-intervention (2010 –2011) and intervention (2012–2013) periods, using an interrupted time-se...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
In this study, we applied three easier, faster, and cost-effective methods including PCR-based open reading frames (ORFs) typing, sequence typing of blaOXA-51-like and RAPD-PCR method to rapid typing of A. baumannii strains. Taken together in the present study the results of ORFs typing, PCR-sequencing of blaOXA-51-like genes and MLST sequence typing revealed there was a high prevalence (62%, 35/57) of ST2 as international and successful clone which detected among clinical isolates of multi-drug resistant A. baumannii with ORF pattern B and blaOXA-66 gene. Only 7% (4/57) of MDR isolates belonged to ST1 with ORF pattern A a...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
Abstract Dissemination of carbapenem-resistant Acinetobacter baumannii (CRAB) is mainly due to the spread of clonal lineages, particularly those included into the clonal complexes (CC) CC1, CC2, CC15, CC25, and CC79. We evaluated the usefulness of a recently modified PCR-based trilocus sequence-based typing (m3LST) in comparison with the standard multilocus sequence typing (MSLT) of 7 housekeeping genes as per the Institute Pasteur Scheme to assign the clonal complexes in CRAB. A collection of 78 CRAB isolated from 67 different Brazilian health institutions was submitted to both methodologies, and concordance rate...
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
Publication date: July 2017 Source:Microbial Pathogenesis, Volume 108 Author(s): Ali Mohammadi Bardbari, Mohammad Reza Arabestani, Manoochehr Karami, Fariba Keramat, Mohammad Yousef Alikhani, Kamran Pooshang Bagheri Acinetobacter baumannii potential to form biofilm and exhibit multiple antibiotic resistances may be responsible in its survival in hospital environment. Accordingly, our study was aimed to determine the correlation between ability of biofilm formation and the frequency of biofilm related genes with antibiotic resistance phenotypes, and also the categorization of their patterns in clinical and environmental is...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Future Microbiology Ahead of Print.
Source: Future Microbiology - Category: Microbiology Source Type: research
CONCLUSIONS: High rate of anti-dengue IgM seropositivity was reported in our study. The environmental bacteria were predominantly isolated and identified in A. aegypti. The paratransgenic approach to control vector might be possible by spreading the genetically modified bacteria in larval habitat or shelter of adult mosquitoes. PMID: 28193261 [PubMed - in process]
Source: Journal of Health, Population, and Nutrition - Category: Global & Universal Authors: Tags: J Health Popul Nutr Source Type: research
Abstract BackgroundWe assessed the impact of intensified infection control measures (ICM) on colonization and infection caused by carbapenem‐resistant (CR) Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii in a Solid Organ Transplantation (SOT) Department. MethodsA quasi‐experimental methodology was followed. The study was divided in 3 periods: pre‐intervention, intervention with implementation of an ICM bundle including active surveillance program (ASP) and gradually enhanced measures, and post‐ASP without ASP. The bundle included active surveillance cultures, contact precautions, hand hyg...
Source: Transplant Infectious Disease - Category: Transplant Surgery Authors: Tags: Original Report Source Type: research
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