Clinical profile and satisfaction with anticoagulated treatment in patients with non-valvular atrial fibrillation attended in Internal Medicine and Neurology departments of Spain.
CONCLUSIONS: Although there were some differences in the clinical profile of patients with atrial fibrillation attended in Neurology or Internal Medicine departments, all of them had many comorbidities and a high thromboembolic risk. Despite INR control was poor, the most common oral anticoagulant used were vitamin K antagonists. Satisfaction related to oral anticoagulation was high. PMID: 28990646 [PubMed - in process]
Conclusion: The knowledge about hypertension among majority of patients was reasonable. But they were unaware of their disease status. The drug compliance among them was poor. Forgetfulness and interruptions of daily routine were common reasons attributed for nonadherence. PMID: 29230325 [PubMed]
A new study finds a strong link between CHF readmissions after transcatheter aortic-valve implantation and mortality but no easy answers on how to avert it.Medscape Medical News
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Authors: Huang H, Shetty S, Bauer E, Lang K Abstract OBJECTIVE: To estimate the proportion of patients with moderate to severe chronic kidney disease (CKD) whose initial DPP4-i dosage was concordant with prescribing information (label) recommendations in the United States. METHODS: Adult patients with T2DM who initiated a DPP4-i (linagliptin, sitagliptin, saxagliptin) between Jan 1, 2011 and Jun 30, 2014 were identified using electronic medical records and administrative claims, with index date being the date of first observed DPP4-i treatment. Patients were required to have CKD Stage 3b, 4 or 5 (eGFR value
Conclusions: In diabetic patients with NAFLD, light or moderate lifetime alcohol consumption was not significantly associated with liver fibrosis. The impact of lifetime alcohol intake on fibrosis progression and diabetic comorbidities, in particular obstructive sleep apnea and hypertriglyceridemia, requires further investigation. PMID: 29226116 [PubMed - in process]
The new ACC/AHA guidelines for hypertension lowered the threshold for a diagnosis of hypertension. Are these changes justified?Georgetown University Family Medicine
Conclusion Community screening for AF with SL-ECG was feasible and it identified a significant proportion of citizens with newly diagnosed AF. The prevalence of AF in a Chinese population in Hong Kong was comparable with that of contemporary Western counterparts. Apart from age and sex, different anthropometric parameters and cardiovascular comorbid conditions were identified as independent predictors of AF.
Abstract PURPOSE: The purpose of this study is to report on the effect of using CHA2DS2VASc (congestive heart failure, hypertension, age ≥75 years [doubled], type 1 or type 2 diabetes mellitus, stroke or transient ischemic attack or thromboembolism [doubled], vascular disease [prior myocardial infarction, peripheral artery disease, or aortic plaque], age 65-75 years, sex category [female]) rather than CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, and prior stroke) to determine candidacy for anticoagulant prophylaxis in insured patients with atrial fibrillation (AF). M...
Hypertension is a major risk factor for cardiovascular disease in the elderly.1 Hypertension occurs in 69% of persons with a first myocardial infarction,2 in 77% of those with a first stroke,2 in 74% of individuals with congestive heart failure,2 and in 60% of older adults with peripheral artery disease.3 Hypertension is also a major risk factor in older adults for dissecting aortic aneurysm, sudden cardiac death, angina pectoris, chronic kidney disease, left ventricular hypertrophy, thoracic and abdominal aortic aneurysms, atrial fibrillation, diabetes mellitus, the metabolic syndrome, vascular dementia, Alzheimer disease...
The disease and cost burden of atrial fibrillation (AF) is expected to double over the next 25 years (1). With availability of newer therapies, efforts to refine the triage of who receives therapies, when, and for how long have assumed center stage. Over the last few years, a host of new scores such as CHADS-VASc (congestive heart failure [or Left ventricular systolic dysfunction], hypertension, age≥75 years, diabetes, prior Stroke, TIA, or thromboembolism, vascular disease [e.g. peripheral artery disease, myocardial infarction, aortic plaque], age 65–74 years, sex category) and ATRIA (Anticoagulation and Ris...