Arginine Modification of Lycosin-I to Improve Inhibitory Activity Against Cancer Cells.
Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02233F, PaperPeng Zhang, Jing Ma, Yujie Yan, Bo Chen, Bobo Liu, Cui Jian, Baode Zhu, Song ping Liang, Youlin Zeng, Zhonghua Liu Lycosin-I is a linear amphipathic [small alpha]-helical anticancer peptide (ACP) extracted from the spider Lycosa singoriensis, which can activate the mitochondrial death pathway to induce apoptosis in tumor cells and up-regulate... The content of this RSS Feed (c) The Royal Society of Chemistry
CONCLUSION: TAVR with a balloon-expandable system is safe and effective and can be used for patients with severe AS in China. It requires careful patient selection and preoperative assessment so as to reduce the 30-day postoperative mortality rate. PMID: 29236149 [PubMed - as supplied by publisher]
New J. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7NJ04266C, PaperMariana Lozano Gonzalez, Maria Teresa Ramirez-Apan, Antonio Nieto-Camacho, Ruben Alfredo Toscano, Cecilio Alvarez Toledano A novel series of (Z)-2-(hydroxy(aryl)methylene)-2,3-dihydro-1H-indanone derivatives were designed, synthesized and evaluated as cytotoxic agents against six cancer cell lines. In vitro studies showed that most of the molecules exhibited significant... The content of this RSS Feed (c) The Royal Society of Chemistry
We report pulmonary resections for lung cancers in 2 patients with partial anomalous pulmonary venous connection (PAPVC) identified preoperatively. In case 1, right upper lobectomy was performed as the definitive operation for both lung cancer and PAPVC in the same lobe. In case 2, because lung cancer and PAPVC existed in different lobes, cardiac catheterization was performed to evaluate the need for correction of the PAPVC. Then, left lower lobectomy was safely performed without correcting the PAPVC located in the left upper lobe. The treatment plan for patients with PAPVC who require pulmonary resection should be careful...
PMID: 29233347 [PubMed - in process]
ConclusionsOur studies provide strong rationale for the near‐term development of specific HDAC3 inhibitors for the treatment of CRPC.
Unfortunately some children have to spend Christmas in hospital and to make the day a little bit brighter seven-year-old Aroha White, is making stockings for children on her cancer ward in Perth.
Pioneering psychiatrist in learning disability. She was born in Isleworth, UK, on April 10, 1939, and died of cancer in Stalbridge, UK, on June 12, 2017, aged 78 years.
Most women tend to overestimate their risk of breast cancer, according to research...Read more on AuntMinnie.comRelated Reading: At-risk women not receiving breast MRI scans Mammo recalls don't keep women from other tests Most women prefer annual breast cancer screening Women still value mammography's benefits over 'harms' Simple interventions reduce mammography recall rates
Authors: Sabang RL, Gandhiraj D, Fanucchi M, Epelbaum O Abstract INTRODUCTION: Malignant pleural effusion (MPE) is a feature of metastatic cancer that is associated with significant morbidity and healthcare costs. The typical current management of MPE involves the combination of systemic chemotherapy and mechanical intervention in the pleural space. Vascular endothelial growth factor (VEGF), an extremely potent inducer of vascular permeability, has been shown to mediate fluid formation in pleural malignancy. Therefore, bevacizumab, an inhibitor of VEGF activity, offers theoretical promise as a means of abolishing f...
Conclusion: If the patient is able to retry anticoagulation therapy and the filter is no longer needed, the filter should be removed, even if a long time has elapsed since implantation. If the filter cannot be removed, it is recommended that follow-up computed tomography be performed regularly to monitor the progress of venous thromboembolisms as well as any filter-related complications. PMID: 29234611 [PubMed]