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Arginine Modification of Lycosin-I to Improve Inhibitory Activity Against Cancer Cells.

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02233F, PaperPeng Zhang, Jing Ma, Yujie Yan, Bo Chen, Bobo Liu, Cui Jian, Baode Zhu, Song ping Liang, Youlin Zeng, Zhonghua Liu Lycosin-I is a linear amphipathic [small alpha]-helical anticancer peptide (ACP) extracted from the spider Lycosa singoriensis, which can activate the mitochondrial death pathway to induce apoptosis in tumor cells and up-regulate... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research

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CANCER patients could be boosted in their fight against the condition by cutting back on sugary foods, scientists have revealed.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Daisy O'Leary Pye, 12, from Lee, south-east London, was diagnosed with Hodgkin's lymphoma, a type of cancer that develops in the lymphatic system, after shooting billboard and television ads.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Johnson DR, Omuro AMP, Ravelo A, Sommer N, Guerin A, Ionescu-Ittu R, Shi S, Macalalad A, Uhm JH Abstract OBJECTIVE: Glioblastoma (GBM) is an aggressive disease with limited therapeutic options. While bevacizumab was approved in 2009 for the treatment of patients with progressive GBM, its impact on overall survival (OS) remains unclear. Using US population-based cancer registry data (SEER), this study compared OS of patients diagnosed with GBM before and after bevacizumab approval. METHODS: Adult patients from SEER with a GBM diagnosis were divided into two cohorts: patients diagnosed in 2006-2008 (Pre-...
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
[Abstract unavailable] Language: en...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Professor Kefah Mokbel, of the Princess Grace Hospital in central London, found that women who colour their hair are 14 per cent more likely to suffer breast cancer.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
[New Times] Haston Charlotte talks with a calm and confident endearing voice, sharing her story of how she survived one of the deadliest diseases, cancer. The 50-year old mother of one from Kagugu in Gasabo District was able to beat breast cancer, thanks to early diagnosis and treatment which was administered when the disease was still in its first stage. "I was lucky to get early diagnosis and treatment before the disease had spread and in its first stage, before the worst could happen," she says.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
[Daily News] AS cases of cervical cancer increase, screening services with existing family planning clinics can increase access to the services and treatment.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
CONCLUSION: Performance rates of DRE and PSA testing by doctors who are not urologists are very low, which may have significant clinical implications. It is recommended that SA prostate cancer screening guidelines are necessary to change practice with regard to this condition. PMID: 29025456 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
CONCLUSIONS: HIV-infected patients were younger than those who were not infected, and presented at a more locally advanced stage of disease. HIV infection was an independent predictor for CIN. HIV-infected patients had an almost two-fold increased risk of developing CIN and developed neutropenia at a much faster rate. A high baseline white cell count and ANC were protective against CIN. PMID: 29025449 [PubMed - in process]
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
CONCLUSION: The study demonstrated a marked inconsistency between recall and recognition of signs of childhood cancer, with signs of CNS malignancies being least recognised. However, the majority of students could recognise enough early warning signs to meet the university pass standard. Although this study demonstrated acceptable recognition of early warning signs of childhood cancer at one university, we suggest that long-term recall in medical practitioners is poor, as reflected in the low age-standardised ratios of childhood cancer in SA. We recommend increased ongoing exposure to paediatric oncology in medical school ...
Source: South African Medical Journal - Category: African Health Tags: S Afr Med J Source Type: research
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