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4 ‐bp insertion/deletion (rs3783553) polymorphism within the 3'UTR of IL1A contributes to the risk of prostate cancer in a sample of Iranian Population

In conclusion, our findings proposed an association between IL1A 4‐bp ins/del polymorphism and PCa risk. Additional studies with enlarged sample size and diverse ethnicities are required to validate our finding. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Biochemistry - Category: Biochemistry Authors: Tags: Article Source Type: research

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ConclusionsOur studies provide strong rationale for the near‐term development of specific HDAC3 inhibitors for the treatment of CRPC.
Source: The Prostate - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Conclusions This review highlights the need to conduct more robust studies to provide conclusive evidence on the effectiveness of different interventions to improve men’s screening behavior.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
In this study, we compared fresh frozen, formalin-fixed paraffin-embedded (FFPE), and PAXgene-fixed paraffin-embedded (PFPE) tissue preparation methods in radical prostatectomy prostate tissue from 36 patients and performed a preliminary test of feasibility of using PFPE tissue in routine prostate surgical pathology diagnostic assessment. In addition to comparing histology, immunohistochemistry, and general measures of DNA and RNA integrity in each fixation method, we performed functional tests of DNA and RNA quality, including targeted Miseq RNA and DNA sequencing, and implemented methods to relate DNA and RNA yield and q...
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research
Conclusions: Radium-223 showed a clinical benefit, with a reduction in pain symptoms in 58% of patients. Radium-223 was shown to be an effective and well-tolerated therapeutic option in patients with metastatic CRPC progressing after docetaxel plus prednisone treatment.Oncology
Source: Oncology - Category: Cancer & Oncology Source Type: research
Condition:   Prostate Cancer Intervention:   Drug: Axumin PET/CT Sponsor:   Desert Medical Imaging Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Swedish researchers report an association between acne -- particularly severe acne -- in the late teen years and later prostate cancer risk, a finding that validates other research.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Swedish researchers report an association between acne -- particularly severe acne -- in the late teen years and later prostate cancer risk, a finding that validates other research.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
CONCLUSION: C. longa and curcumin might decrease the risk of cancer and other malignant diseases in the reproductive system. C. longa and curcumin have a protective effect on the reproductive organs activity such as, anti-inflammatory, anti-apoptotic, and antioxidant effects in normal cells but showed pro-apoptotic effects in the malignant cells. Therefore, different effects of C. longa and curcumin are dependent on the doses and the type of cells used in various models studied. PMID: 29232190 [PubMed - in process]
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
A new, life-like 3-D prostate model helps surgeons to rehearse procedures before entering the operating room. The new technology may improve accuracy.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news
MRI scans with a reduced dose of a gadolinium-based contrast agent (GBCA) can...Read more on AuntMinnie.comRelated Reading: GBCA-related allergic reactions rare in cardiac MRI MRI can help avoid unnecessary prostate cancer biopsies NPV is a key indicator for future prostate cancer risk
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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