Effect of Body Mass Index on Exercise Capacity in Patients with Hypertrophic Cardiomyopathy

The objective of this study was to evaluate the relationship between body mass index, exercise capacity, and symptoms in patients with hypertrophic cardiomyopathy (HC) and to utilize results of cardiopulmonary exercise tests (CPX) and transthoracic echocardiograms to understand the mechanism(s) of reduced exercise capacity across body mass index groups. Over a 6 year period, 510 consecutive patients with HC seen at a tertiary referral center underwent CPX and a transthoracic echocardiogram. Increasing body mass index (BMI) was associated with decreased exercise capacity as assessed by peak VO2 (mL/kg/min).

Source: The American Journal of Cardiology - October 11, 2017 Category: Cardiology Authors: Carolyn M. Larsen, Caroline A. Ball, Virginia B. Hebl, Kevin C. Ong, Konstantinos C. Siontis, Thomas P. Olson, Michael J. Ackerman, Steve R. Ommen, Thomas G. Allison, Jeffrey B. Geske Source Type: research