Alcohol's Effects on the Cardiovascular System.
Alcohol's Effects on the Cardiovascular System. Alcohol Res. 2017;38(2):219-241 Authors: Piano MR Abstract Alcohol use has complex effects on cardiovascular (CV) health. The associations between drinking and CV diseases such as hypertension, coronary heart disease, stroke, peripheral arterial disease, and cardiomyopathy have been studied extensively and are outlined in this review. Although many behavioral, genetic, and biologic variants influence the interconnection between alcohol use and CV disease, dose and pattern of alcohol consumption seem to modulate this most. Low-to-moderate alcohol use may mitigate certain mechanisms such as risk and hemostatic factors affecting atherosclerosis and inflammation, pathophysiologic processes integral to most CV disease. But any positive aspects of drinking must be weighed against serious physiological effects, including mitochondrial dysfunction and changes in circulation, inflammatory response, oxidative stress, and programmed cell death, as well as anatomical damage to the CV system, especially the heart itself. Both the negative and positive effects of alcohol use on particular CV conditions are presented here. The review concludes by suggesting several promising avenues for future research related to alcohol use and CV disease. These include using direct biomarkers of alcohol to confirm self-report of alcohol consumption levels; studying potential mediation of various genetic, socioeconomic, and racial and eth...
CUTTING down on how much we drink could slash the risk of dementia by a third. Scientists say heavy boozing is a “major factor” in all forms of the incurable illness, having looked at 57,000 cases of dementia diagnosed before 65.
CONCLUSIONS: The level of patient satisfaction, duration of hospitalisation and the severity of stroke were found to be the three important factors associated with SS-QOL at hospital discharge, indicating doctors might assist patients adjust to the consequences of stroke and improve the QOL of subacute stroke. PMID: 29457918 [PubMed - as supplied by publisher]
CONCLUSIONS Maternal-fetal risks are increased in pregnancies in conjunction with CGN patients. Prenatal proteinuria ≥3.5 g/d, BP ≥160/110 mmHg, and uric acid ≥363 μmol/L were the maternal and fetal risk predictors in pregnancy. PMID: 29455212 [PubMed - in process]
CONCLUSION: findings should be interpreted cautiously, due to limited and poor-quality evidence. Rigorously designed further research of the psychosocial interventions targeting predictive demographic variables is recommended. PMID: 29457938 [PubMed - in process]
Grants to support research involving federally recognized tribes or tribal-based organizations on issues of crime and justice, with research priorities including alcohol and and other substance abuse and violent crime/victimization. Geographic coverage: Nationwide -- National Institute of Justice, U.S. Department of Justice
New research, which was presented at the American Association for the Advancement of Science’s annual conference, has found that moderate drinking is linked to a longer life. Drinking about two glasses of wine or beer a day was linked to an 18% drop in a person’s risk of early death—an even stronger effect than the life-preserving practice of exercise, according to the researchers. The results came from the 90+ Study, a research project out of the University of California Irvine’s Institute for Memory Impairments and Neurological Disorders that examines the habits of people who live to at least 90. ...
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Heavy alcohol use in teens leads to long-lasting structural and genetic changes in the brain that may be reversed with a short course of donepezil, early research suggests.Medscape Medical News
Experts say 'booze is booze' and 'diet' cocktails, which are filled with chemicals, can ultimately have the same impact on the waistline as a regular alcoholic drink.
Condition: Parkinson Disease Interventions: Drug: Clarithromycin; Drug: Placebo Sponsors: Nicolaas Bohnen, MD, PhD; National Institute of Neurological Disorders and Stroke (NINDS) Recruiting