Corrected QT Interval and Methadone Dose and Concentrations in Pregnant and Postpartum Women.

CONCLUSIONS: QTc correlated with dose and R-methadone concentration during the third trimester. However, longer QTc was common among women during and after pregnancy. Given the relatively high rate of QTc > 450 ms, an ECG before and after methadone initiation is advisable for pregnant and postpartum women. PMID: 28994902 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28994902?dopt=Abstract

Source: Journal of Clinical Psychiatry - October 11, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research