Sigma-1 receptor agonist increases axon outgrowth of hippocampal neurons via voltage-gated calcium ions channels.

CONCLUSION: Sig-1R activation can enhance axon outgrowth and may have a substantial influence on neurogenesis and neurodegenerative diseases.
PMID: 28990373 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - October 8, 2017 Category: Neuroscience Authors: Li D, Zhang SZ, Yao YH, Xiang Y, Ma XY, Wei XL, Yan HT, Liu XY Tags: CNS Neurosci Ther Source Type: research