Incidence and Recurrence of Allergic Fungal Sinusitis at Tertiary Care Facility

AbstractTo assess the incidence and recurrence of patients of allergic fungal sinusitis after administration of topical steroids for 24  months this is a cross-section study. Total 90 patients diagnosed with nasal pathology were enrolled from January 2011 to December 2015 at Liaquat National Hospital, various sign and symptoms were tabulated. Patients clinical, radiological and histopathological reports were analyzed. Post operativ e steroid dose and recurrence rate was noted. Post stratification, Chi-square test and Fisher’s exact test was applied to see the association between CT Scan and endoscopic findings and recurrence consideringP value  ≤ 0.05 as significant. Total 90 patients of either sex aged between 12 and 63 years fulfilled the inclusion criteria and were enrolled in the study. The results showed that among all study patients, 53(58.9%) were male and 37(41.1%) were female. Common presenting symptoms included nasal obstru ction, nasal discharge&headache followed by proptosis. From 90 cases, 73(81.2%) had chronic rhinosinusitis and 17(18.9%) cases had Aspergillus. Postoperatively patients were given topical steroids and recurrence was seen in twelve (17.8%). All were aspergillus positive. The incidence of AFRS is (17) 18.9% of CRS which is slightly higher as reported in previous literature. Endoscopic finding may differ from CT scan finding. Patients presented with CRS should receive steroids for at least 2  years to prevent re...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research

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Publication date: Available online 25 January 2019Source: Journal of Clinical and Experimental HepatologyAuthor(s): Lawrence AJ, Naveen Kalra, Anmol Bhatia, Radhika Srinivasan, Ajay Gulati, Rakesh Kapoor, Vikas Gupta, Radha K. Dhiman, Yogesh Chawla, Niranjan KhandelwalAimThe aim of this study was to compare the diagnostic adequacy of computed tomography (CT)–ultrasound (US) fusion image–guided fine needle aspiration (FNA) and US-guided FNA in patients with suspected hepatic metastases.MethodsThirty consecutive patients of either sex with known or unknown primary malignancy suspected of having liver metastases o...
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
ConclusionA small proportion of ED patients discharged with nonspecific diagnoses of headache or back pain returned with a serious neurologic condition or inhospital death within 30 days.
Source: Annals of Emergency Medicine - Category: Emergency Medicine Source Type: research
Publication date: Available online 21 February 2019Source: The Saudi Dental JournalAuthor(s): Muneera Abdulaziz AlHassan, Ahmed Fathi AlOmar, Rana Saud AlShagroudAbstractBackgroundSalivary glands swellings are frequently encountered in the dental clinic. Their causes include but not limited to neoplasm, infection, stone, and inflammation. Sublingual salivary gland enlargements are commonly caused by ranula, while neoplasms rarely occur and if found they tend to be malignant. Another cause is idiopathic hyperplasia of the sublingual gland (IHSG), which is characterized as asymptomatic swelling of unknown cause, protrude fro...
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
ConclusionDental implants complications are not uncommon. managing such complications are important to prevent serious complications. Non dental manifestations can also occur, such as this case, where chronic headache and sinusitis were observed. Accurate locating of the specific site of implant placement and knowledge of the anatomical landmark are important. Displaced dental implants into the maxillary sinus must be removed as soon as possible to avoid further complications.
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
In conclusion,in vitro application of physiological levels of cyclic strain to tissue engineered heart valves seeded with autologous endothelial cells would be advantageous.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research
This study concerns the perceived roughness of 3D printed material samples (print process: fused deposition modelling, or FDM), generated across changes in print speed, build angle, and layer height. Physical sample surface roughness parameters Ra and Rq were first obtained via optical scanning. Next, using a custom-designed apparatus, surface roughness perception was assessed via a psychophysical procedure that identified the just noticeable difference in roughness through the sense of touch alone. By comparing both data sets, this study concludes that for FDM-printed materials, objective surface roughness parameters (Ra,...
Source: Materials Today Communications - Category: Materials Science Source Type: research
Authors: Dalvadi H, Parmar K, Yadav S Abstract Bicalutamide (BCT), an anticancer drug, suffers from dissolution rate limited bioavailability and poor micromeritic properties. Spherical crystallization involves formation of spherical agglomerates with enhanced dissolution properties, obviating the need of further granulation process. The present investigation was focused on spherical agglomeration of BCT by quasi emulsion solvent diffusion method. All the responses were subjected to principal component analysis to scrutinize the critical attributes. Further for optimization, X1; influence of phase ratio, X2; amount ...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
We report a case of Scedosporium apiospermum (S. apiospermum) CIFR with an atypical clinical and radiological presentation.Case reportA 72-year-old immunocompetent man presented with chronic headache, neck pain and bilateral limitation of lateral gaze. Imaging revealed an isolated left sphenoidal lesion with marked bone changes and an extradural abscess over the clivus. Large endoscopic sphenoidotomy with type II rhinopharyngectomy was performed and the diagnosis of S. apiospermum CIFR was based on histological examination and fungal culture. The patient refused all medical treatment and did not present any ...
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - Category: ENT & OMF Source Type: research
In conclusion, invasive aspergillosis should be included in the differential diagnosis of SCD patients with central nervous system (CNS) lesions. PMID: 30251738 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
Discussion by Dr MGK Murthy, Dr GA Prasad      Cavernous sinus is extradural venous plexus surrounded by a dural fold in the middle cranial fossa containing internal carotid artery with its periarterial sympathetic plexus, abducens nerve lateral to the internal carotid artery, but medial to the oculomotor and trochlear nerves and the ophthalmic and maxillary divisions of the trigeminal nerve, which run superior to inferior within the lateral dural border of the cavernous sinus.     Thrombosis of the cavernous sinus is usually caused by bacterial or fungal invasion comp...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
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