Incidence and Recurrence of Allergic Fungal Sinusitis at Tertiary Care Facility

AbstractTo assess the incidence and recurrence of patients of allergic fungal sinusitis after administration of topical steroids for 24  months this is a cross-section study. Total 90 patients diagnosed with nasal pathology were enrolled from January 2011 to December 2015 at Liaquat National Hospital, various sign and symptoms were tabulated. Patients clinical, radiological and histopathological reports were analyzed. Post operativ e steroid dose and recurrence rate was noted. Post stratification, Chi-square test and Fisher’s exact test was applied to see the association between CT Scan and endoscopic findings and recurrence consideringP value  ≤ 0.05 as significant. Total 90 patients of either sex aged between 12 and 63 years fulfilled the inclusion criteria and were enrolled in the study. The results showed that among all study patients, 53(58.9%) were male and 37(41.1%) were female. Common presenting symptoms included nasal obstru ction, nasal discharge&headache followed by proptosis. From 90 cases, 73(81.2%) had chronic rhinosinusitis and 17(18.9%) cases had Aspergillus. Postoperatively patients were given topical steroids and recurrence was seen in twelve (17.8%). All were aspergillus positive. The incidence of AFRS is (17) 18.9% of CRS which is slightly higher as reported in previous literature. Endoscopic finding may differ from CT scan finding. Patients presented with CRS should receive steroids for at least 2  years to prevent re...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - Category: ENT & OMF Source Type: research

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CONCLUSIONS: The present study provides a working example of the applicability of functional PET imaging as a suitable tool to determine PK parameters in small animals. The comparative analysis in the current study demonstrates that it is feasible to use [18F]FDG PET and [18F]FAZA PET in the same model to analyze their blood PK parameters, and to estimate kinetic parameters for these tracers in tumor. This non-invasive imaging-based determination of tissue kinetic parameters facilitates translation from pre-clinical to clinical phases of drug development. This article is open to POST-PUBLICATION REVIEW. Registered rea...
Source: J Pharm Pharm Sci - Category: Drugs & Pharmacology Authors: Tags: J Pharm Pharm Sci Source Type: research
Publication date: February 2019Source: Carbon, Volume 142Author(s): Yanli Nan, Bo Li, Xiaolong Song, Noriaki SanoAbstractWe firstly reveal the unique tendency in the capacitance of an electric double layer capacitor (EDLC) made of single-walled carbon nanohorns (SWCNHs), where there is an optimized value of specific surface area (SSA) to achieve the high capacitance value at a high charge-discharge rate. As a result, in the experimental observation, SWCNHs treated by oxidation in air at 550 °C can exhibit 963.4 m2/g of SSA and 286.6 F/g of EDLC capacitance, whereas the ones treated at 500 °C can exhibit 797...
Source: Carbon - Category: Materials Science Source Type: research
Authors: Kumar NS, Basu S Abstract The classical bone scan findings of Rhabdomyolysis is presented in this illustration. A 60 year old female patient with complaints of low backache and bilateral lower limbs weakness over 1 year was referred for whole body skeletal status evaluation. Whole body skeletal scintigraphy undertaken 3 hrs after I.V injection of 15 mci of 99mTc-MDP revealed bilaterally symmetrical diffuse skeletal muscle tracer activity in deltoid, lattisimus dorsi, diaphragm, paraspinal muscles, gluteus muscles and muscles of thigh. On biochemical investigations for evaluation of skeletal muscle uptake r...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Conclusion: Diagnosis of CNS TB should be based on clinical features and 3 or more supportive criteria rather than CSF positivity on staining or culture. Rapid and early diagnosis by positive CSF PCR and CT/MRI findings should replace CSF AFB staining and culture in further for the diagnosis of CNS TB. PMID: 30341844 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Carotid artery disease is a major cause of stroke. The in vivo computed tomography calcified and noncalcified plaque structural components that connote carotid plaque rupture and symptoms remain ill-defined for a given degree of stenosis. We therefore analyzed computed tomography angiography (CTA) images of symptomatic patients enrolled in the Plaques at Risk (PARISK) study designed to determine the natural history of carotid stenosis (30%-70%) causing ipsilateral neurologic events.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
The objective of this study was to test and to compare the in vitro performance of balloon-expandable covered stents having the indication for use in renal arteries as chimney grafts.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
The objective of this study was to determine the cause and anatomic patterns of recurrent varices after endovenous laser ablation (EVLA).
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
ConclusionsThe two main contributors to the difference between dosimetry calculations using MAA versus 90Y PET/MRI can be attributed to the changes in catheter positioning as well as the liver ROIs used for the calculations. In spite of these differences, our results demonstrate that the dosimetry values obtained from pre-therapy MAA SPECT/CT scans and PET/MRI post-therapy 90Y studies were not significantly different.
Source: European Journal of Radiology - Category: Radiology Source Type: research
In conclusion, invasive aspergillosis should be included in the differential diagnosis of SCD patients with central nervous system (CNS) lesions. PMID: 30251738 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
Discussion by Dr MGK Murthy, Dr GA Prasad      Cavernous sinus is extradural venous plexus surrounded by a dural fold in the middle cranial fossa containing internal carotid artery with its periarterial sympathetic plexus, abducens nerve lateral to the internal carotid artery, but medial to the oculomotor and trochlear nerves and the ophthalmic and maxillary divisions of the trigeminal nerve, which run superior to inferior within the lateral dural border of the cavernous sinus.     Thrombosis of the cavernous sinus is usually caused by bacterial or fungal invasion comp...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
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