γ‐Aminobutyric acid (GABA) oral rinse reduces capsaicin‐induced burning mouth pain sensation: An experimental quantitative sensory testing study in healthy subjects

ConclusionsCapsaicin‐induced burning tongue pain and decreases in WDT and HPT can be ameliorated by rinsing the mouth with lidocaine and GABA solutions. SignificanceRinsing the mouth with an oral GABA containing solution ameliorated burning pain and increased heat sensitivity produced by application of capsaicin to the tongue. This finding suggests that GABA can act as a local analgesic agent in the oral cavity.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fejp.1128

Source: European Journal of Pain - October 11, 2017 Category: Anesthesiology Authors: Y. Zhang, K. Wang, L. Arendt ‐Nielsen, B.E. Cairns Tags: Original Article Source Type: research