Compton camera study for high efficiency SPECT and benchmark with Anger system.

In this study we compare a commercial SPECT-Anger device, the General Electrics
 Healthcare Innia system with a High Energy General Purpose (HEGP) collimator,
 and the Compton camera prototype under development by the French collaboration
 CLaRyS, through Monte Carlo simulations (GATE - GEANT4 Application for
 Tomographic Emission - version 7.1 and GEANT4 version 9.6, respectively). Given
 the possible introduction of new radio-emitters at higher energies intrinsically allowed
 by the Compton camera detection principle, the two detectors are exposed to point-
 like sources at increasing primary gamma energies, from actual isotopes already
 suggested for nuclear medicine applications. The Compton camera prototype is rst
 characterized for SPECT application by studying the main parameters aecting its
 imaging performance: detector energy resolution and random coincidence rate. The
 two detector performances are then compared in terms of radial event distribution,
 detection eciency and nal image, obtained by gamma transmission analysis for
 the Anger system, and with an iterative List Mode-Maximum Likelihood Expectation
 Maximization (LM-MLEM) algorithm for the Compton reconstruction.
 The results show for the Compton camera a detection eciency increased by a factor
 larger than an order of magnitude with respect to the Anger camera, associated with&am...
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research