Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model.

In conclusion, the secretome from hypoxia-conditioned ADMSCs facilitates the repair of gastric mucosal injury through the enhancement of angiogenesis and re-epithelization, as well as the activation of COX2-PGE2 axis with a paracrine activity involving CCL-20 factor. PMID: 28993190 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28993190?dopt=Abstract

Source: Biochimica et Biophysica Acta - October 6, 2017 Category: Biochemistry Authors: Xia X, Chiu PWY, Lam PK, Chin WC, Ng EKW, Lau JYW Tags: Biochim Biophys Acta Source Type: research