The role of human papillomavirus in p16 positive oral cancers

ConclusionWe have shown that the presence of transcriptionally active HPV rarely occurs in OSCC and that p16 is not an appropriate surrogate marker for HPV in OSCC cases. We propose that non‐viral mechanisms are responsible for the majority of IHC p16 overexpression in OSCC.This article is protected by copyright. All rights reserved.

Source: Journal of Oral Pathology and Medicine - October 1, 2017 Category: Pathology Authors: Simone Belobrov, Alyssa M. Cornall, Richard J. Young, Kendrick Koo, Christopher Angel, David Wiesenfeld, Danny Rischin, Suzanne M. Garland, Michael McCullough Tags: Original Article Source Type: research