Experimental Study of the Protective Effect of Simvastatin on Lung Injury in Rats with Sepsis

In conclusion, simvastatin improved endothelial permeability and mitigated the inflammatory response of lung tissue, the oxidative stress response, and cell apoptosis by inhibiting the TLR4/NF- κB signaling pathway, thereby alleviating sepsis-induced acute lung injury in rats.

http://link.springer.com/10.1007/s10753-017-0668-4

Source: Inflammation - October 11, 2017 Category: Allergy & Immunology Source Type: research