Increased levels of sodium chloride directly increase osteoclastic differentiation and resorption in mice and men

ConclusionsThe reported that enhanced bone resorption after high-sodium diets may not only be secondary to the urinary calcium loss but may also be a direct, cell-mediated effect on osteoclastic resorption. These findings allow us to suggest an explanation for the clinical findings independent of a PTH-mediated regulation.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research