Syndrome of inappropriate anti-diuresis induces volume-dependent hypercalciuria

ConclusionsOur results show that SIAD results in a volemic expansion tendency that is associated with a decrease in renal calcium reabsorption and thus hypercalciuria, whereas in the hypovolemic group, calciuria was not increased. Therefore, renal loss of calcium and bone demineralization in SIAD patients could be partly induced by volemic expansion.

http://link.springer.com/10.1007/s00198-017-4186-x

Source: Osteoporosis International - October 11, 2017 Category: Orthopaedics Source Type: research