Medtronic breaks ground on western China Innovation Center
Medtronic (NYSE:MDT) said today it has begun work on an Innovation Center in Chengdu, China, slated to open in 2020. The new Chengdu Innovation Center is being built at the Singapore-Sichuan Hi-Tech Innovation Park in the Sichuan Province and aims to provide clinical training and research platforms for medical workers in the region and neighboring regions. “Medtronic understands the critical role that rural physicians play in driving the healthcare availability and transformation. As such, we hope to support the growth and development of medical workers in China’s vast central and western regions, help them better understand, grasp and capitalize the frontier technologies, enhance their clinical skills to benefit more patients, and move forward together toward the Healthy China goal,” Medtronic CEO Omar Ishrak said in a prepared statement. Medtronic said that despite improved clinical training investments, training in China’s western regions “remains insufficient” and has created an average 10-year gap between the maturation period of Chinese physicians and those in developed countries. “Chengdu is actively fostering innovation within the biopharmaceutical industry, and it’s particularly important to build an open and pragmatic innovation environment. We hope that more international leading platforms, like the Medtronic Innovation Center, can inspire innovation and become a driving force in helping us explore loca...
(Wiley) There is substantial international variation in mortality rates after treatment for abdominal aortic aneurysm, or enlargement of the aorta. A BJS (British Journal of Surgery) study that compared 10-year data from England and Sweden found that mortality rates were initially better in Sweden but improved over time alongside greater use of a minimally invasive procedure called endovascular aneurysm repair in England. Now there is no difference between postoperative mortality rates after aneurysm repair in England and Sweden.
The incidence of ruptured abdominal aortic aneurysm (AAA) for men>65 years of age has declined by nearly 30% in Finland, likely because of the decrease in AAA prevalence. In addition, the treatment results have improved for both elective and emergency repair and for both open repair and endovascular aneurysm repair (EVAR). The increased use of EVAR has resulted in decreased mortality after elective AAA repair but the late mortality is surprisingly high in comparison with open repair.
Abdominal aortic aneurysm (AAA) represents a major health concern and the curative treatment relies on surgical approaches including open and endovascular aortic repair (EVAR). While epidemiological studies have addressed the major outcomes including mortality and life threatening complications, the impact of surgical intervention on sexual function has been less well described. The aim of this review was to summarise current knowledge on the occurrence of sexual dysfunction in the context of AAA surgical repair and to explore whether surgical techniques could have differential impact.
New and re-designed stent grafts for endovascular aortic aneurysm repair (EVAR) are released regularly. Manufacturers use data from registries to assess stent graft performance, but little is known about the ability of such registries to detect rates of clinically relevant complications. The aim of this paper was to perform a systematic review and meta-analysis to determine pooled failure rates for EVAR stent grafts, to define an acceptable non-inferiority limit for these devices, and then to calculate the number of patients needed for a new device to achieve non-inferiority against published devices.
The aim of this study was to analyse the association between annual hospital procedural volume and post-operative outcomes following repair of abdominal aortic aneurysms (AAA) in Germany.
This study reviews predictors and outcomes of late open surgical conversion for failed EVAR.
We greatly appreciate Ms Barbey's interest in our paper and acknowledge the inherent limitations of retrospective registry-based studies. As for the design of the registry, only data for patients undergoing abdominal aortic aneurysm (AAA) repair are available. Consequently, information on patients not surviving their rupture or on surviving patients who were not considered eligible for repair is missing. Although we acknowledge that this may influence the AAA diameter-at-rupture distribution (namely, larger diameters could carry a greater risk for fatal bleeding), we do not have indications for significant sex-specific inf...
I read with great interest the article recently published by Tomee et al.1 This retrospective registry review proposes a female-specific abdominal aortic aneurysm (AAA) repair threshold, citing the lack of an evidence-based threshold for intervention in women. The proposed female threshold was established by determining the AAA diameter in women that represents the same percentage of rupture compared with the male-specific threshold of 5.5 cm. The use of a mandatory national aneurysm registry strengthens this study by accounting for a variety of institutions and practices.
An 81-year-old man presented to a local general practitioner with complaints of passage of black stools for 3 days, followed by nausea and abdominal discomfort. His medical history included hypertension, hyperlipidemia, and remote smoking. Five years ago he was noted to have a small abdominal aortic aneurysm measuring 35 mm in diameter. While being examined by the local general practitioner, he became hy potensive and had a syncopal episode. Blood analysis showed anemia, with a hemoglobin level of 9.4 g/dL.
This study demonstrates that γδT-cell deficiency inhibits the inflammatory response of vascular tissue and is accompanied by increased ce ll proliferation and decreased apoptosis, thereby resulting in mitigation of AAA.
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