Tests showing low egg reserves not linked to infertility

(Reuters Health) - Lab tests showing that women have low reserves of eggs in their ovaries may not necessarily mean they will struggle to get pregnant, a U.S. study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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AbstractPurposeThe aim of this study is to examine the impact of female body mass index (BMI) on IVF cycle outcomes.MethodsThis is a retrospective cohort study including 51,198 women who initiated their first autologous IVF cycle in 13 fertility centers in the USA between 2009 and 2015. The effect of underweight, overweight, and obese BMI on four different IVF cycle outcomes (cycle cancellation, oocyte and embryo counts, and ongoing clinical pregnancy [OCP]) was evaluated in logistic or Poisson regression analyses with confounders adjusted.ResultsWomen with an overweight or obese BMI experienced worse outcomes than those w...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
ConclusionsThe sealtered sperm proteins and the increased spontaneous acrosome reaction rate might account for this unexplained male infertility in the R-ICSI pregnancy patients. The present proteomic results will throw light on the better understanding of the unexplained infertile mechanisms underlying these normozoospermic man who achieved R-ICSI pregnancy after IVF failure.
Source: Clinical Proteomics - Category: Biochemistry Source Type: research
Conclusion: Our data show that oocyte cytoplasmic abnormalities significantly reduce fertilization achievement in poor responders. PMID: 30119150 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Authors: Vassilopoulou L, Matalliotakis M, Zervou MI, Matalliotaki C, Spandidos DA, Matalliotakis I, Goulielmos GN Abstract The aim of the present review was to discuss a matter of concern in the clinical field of obstetrics/gynecology, namely the potency of in vitro fertilization (IVF) in the management of endometriosis-associated infertility. Endometriosis is a medical condition affecting one tenth of women in their fertile years, and accounts for up to 50% of infertile women. Thus, such high prevalence has established the necessity for investigating the effectiveness of available techniques in eradicating the di...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Most patients going through IVF treatment are fed up of hearing the advice that they should just relax and not get stressed out.Everyone knows that stress is not good for you , and no one chooses to be stressed, but telling people to relax is hardly helpful. After all, how do you implement advice like that? Stress is a completely normal human psychological response – especially when you are going through an expensive  treatment like IVF, where the outcome is so uncertain.I'm a strong believer in the fact that it's not stress which affects fertility - it's the infertility which causes stress . I ’m sure if ...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Many infertile patients get major heartburn when they realize that they aren't able to afford test tube baby treatments because they are so expensive. They can't understand why IVF doctors charge so much, and lots of patients end up thinking of IVF clinics as being greedy.Patients need to understand that part of test tube baby treatment is clinical – and this is what the patient sees. This includes: consultations, blood tests, ultrasound scans, egg collection, and embryo transfer.However, the heart of the IVF treatment is the IVF laboratory, and the patient doesn ’t get to see what goes on behind the scenes in ...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
This study was performed from 2015 to 2017 in the Division of Reproductive Endocrinology and Infertility at Northwestern University. We included patients who became pregnant after IVF-PGS who were seen by the Division of Reproductive Genetics and non-PGS control group.ResultsSixty-eight patients were included. A total of 50 patients (73.5%) opted for non-invasive prenatal screening; 5 (7.4%) had invasive testing (4 had chorionic villus sampling and 1 had amniocentesis). A total of 13 patients (19%) declined further genetic testing. When comparing demographic data, the mean age was significantly higher in the group of patie...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
ConclusionCompared to non-PCOS patients, PCOS patients had greater postoperative ΔBMI and %EWL at 1 year. The majority of patients becoming pregnant after VSG were previously nulliparous. This study shows that VSG is effective for weight loss in PCOS patients with obesity and may positively augment effect fertility rates.
Source: Obesity Surgery - Category: Surgery Source Type: research
Dear science, Today my sons, Oliver and Victor, are 15 years old. It is not a miracle; it is thanks to you. Unable to get pregnant I needed infertility therapy. If you had not isolated the hormones, developed tests, and then designed medications for ovarian stimulation and to trigger ovulation I would never have become pregnant. If ultrasound had not been developed I would not have known I was pregnant with triplets and then what eventually happened next would likely have been even more of a catastrophe. It is sometimes hard to see how these kinds of things helped, but I have not forgotten. I know there is an orchestra inv...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Physician OB/GYN Pediatrics Source Type: blogs
AbstractAlthough assisted reproduction techniques involve the use of semen samples, there is little scientific methodology applied when selecting sperm. To select the most appropriate spermatozoa, first we need to define the optimal molecular characteristics. Sperm lipids may contribute to sperm function, thus our aim was to compare the lipidic profiles of sperm samples used in intracytoplasmic sperm injection cycles that ultimately led to a pregnancy with those that did not.Spermatozoa from infertile patients after intracytoplasmic sperm injection (group non-pregnant,n = 16; vs. group pregnant,n =&thi...
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
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