The reactions of ( μ-H)M3(CO)9(CCSiMe3) (M=Fe, Ru) with thiols: Cleavage of M-M and formation of M-S bonds in isomeric structures

Publication date: 1 November 2017 Source:Journal of Organometallic Chemistry, Volumes 849–850 Author(s): Aldo S. Estrada-Montaño, Ottmar R. Reyes-López, Vianney González-López, Marco A. Leyva, Ana L. Carrasco, A. Vela, Maria J. Rosales-Hoz The reactions of the acetylide trinuclear derivatives [(μ-H)M3(CO)9(CCSiMe3)] (M=Fe, Ru) with the thiols C6H5SH and C6F5SH were carried out. Both reactions lead to the formation of products where cleavage of M-M bonds have occurred. In the case of the iron complex, two products are obtained in the reactions with both thiols: a trinuclear complex of formula [Fe3(CO)9(CCSiMe3)(SR)] (R=C6H5 and C6F5) and a dinuclear compound [Fe2(CO)6(CCSiMe3)(SR) (R=C6H5 and C6F5) which is found as anti and syn isomers in the case of C6H5 and only as the anti isomer in the fluorinated thiol. The reaction with the ruthenium complex under the same conditions gives only decomposition products, but when the reaction with pentafluorothiophenol is carried out in the presence of trimethylamine oxide, total cleavage of M-M bonds takes place to form a mononuclear complex [Ru(CO)3(SC6F5)3]. Spectroscopic and structural characterization of the iron complexes is given. Two isomeric crystal structures were obtained for the trinuclear fluorinated complex. Graphical abstract
Source: Journal of Organometallic Chemistry - Category: Chemistry Source Type: research

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Dalton Trans., 2019, Advance Article DOI: 10.1039/C9DT04234B, CommunicationYangjuan Li, Xiuting Chen, Yu Gong A dinuclear europium complex was synthesizedvia unprecedented deprotonation and oxygen-atom transfer of Me3NO. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in developed countries, and atherosclerosis (AS) is the common pathological basis of many cardiovascular diseases (CVDs) such as coronary heart disease (CHD). The role of the gut microbiota in AS has begun to be appreciated in recent years. Trimethylamine N-oxide (TMAO), an important gut microbe-dependent metabolite, is generated from dietary choline, betaine, and L-carnitine. Multiple studies have suggested a correlation between plasma TMAO levels and the risk of AS. However, the mechanism underlying this relationship is still unclear. In thi...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.9b05383
Source: Journal of Agricultural and Food Chemistry - Category: Food Science Authors: Source Type: research
A novel pathophysiological model of interest is the association between heart failure (HF) and the gastrointestinal system, the ‘gut hypothesis’. The choline and carnitine metabolic by-product, Trimethylamine N-oxide (TMAO) is one of the more prominent molecules associated with the link between HF and the gut. Indeed, TMAO levels are increased in HF populations and higher TMAO levels are associated with poor prognosis, w hereas low TMAO levels either at baseline/follow up confer better prognosis. Considering that TMAO levels seem not to be affected by guideline-HF treatment, this model could represent a novel a...
Source: Heart Failure Clinics - Category: Cardiology Authors: Source Type: research
Publication date: Available online 8 November 2019Source: Food Research InternationalAuthor(s): Tao Wu, Yufang Gao, Junyu Hao, Jieting Geng, Jiaojiao Zhang, Jinjin Yin, Rui Liu, Wenjie Sui, Lingxiao Gong, Min ZhangAbstractThe present study investigated the anti-obesity effects and its mechanism of capsanthin (CAP) in high-fat diet-induced obese C57BL/6J mice. Compared with untreated mice on a high-fat diet for 12 weeks, CAP at 200 mg kg-1 reduced the body weight by 27.5%, significantly reversed glucose tolerance, effectively decreased the serum triglycerides, total cholesterol, low-density lipoprotein cholesterol, and trim...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 11 November 2019Source: Canadian Journal of CardiologyAuthor(s): Yu Tan, Jinying Zhou, Chen Liu, Peng Zhou, Zhaoxue Sheng, Jiannan Li, Runzhen Chen, Li Song, Hanjun Zhao, Bo Xu, Runlin Gao, Hongbing YanAbstractBackgroundTrimethylamine N-oxide (TMAO) has been shown to promote the development of atherosclerosis. However, the relationship between plasma TMAO and neoatherosclerosis, an important underlying mechanism of very late stent thrombosis (VLST), is unknown.MethodsThis post hoc study investigated the association between TMAO and neoatherosclerosis in two independent cohorts. These incl...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ConclusionsThe level of pCS and IS in CSF of PD is higher than expected, based on their blood level. It can influence pathogenesis and progression of PD.Graphical abstract
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Publication date: Available online 10 November 2019Source: Journal of Environmental Chemical EngineeringAuthor(s): Ishan Raj, Ankit Gupta, Amit Bansiwal, A.N. VaidyaAbstractTrimethylamine [TMA] possess various toxic and contributes a hazardous impact on the living organism. The best treatment to eradicate TMA has to be explored and checked. The operation of a biotrickling filter seeded with Agromyces and Ochrobactrum sp. was optimized for degrading trimethylamine [TMA]. The filter bed was adjusted for continuous treating of TMA up to 20 days. The profile of TMA inlet concentration [IC] and air flow rate on the elimination ...
Source: Journal of Environmental Chemical Engineering - Category: Chemistry Source Type: research
o S Abstract Gut dysbiosis and oxidative stress may trigger senile osteoporosis. Fructus Ligustri Lucidi (FLL) has bone-preserving properties and affects the intestinal microecology. However, the mechanism of the anti-osteoporotic effect of FLL and its link to the gut microbiota remains to be elucidated. Here, we demonstrated that sustained exposure of ICR mice to D-galactose / sodium nitrite for 90 days causes aging-related osteoporosis and reduced cognitive performance. The aging phenotype is also characterized by increased oxidative stress in serum. This is likely triggered by abnormal changes in the gut microb...
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
CONCLUSIONS: The level of pCS and IS in CSF of PD is higher than expected, based on their blood level. It can influence pathogenesis and progression of PD. PMID: 31726035 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Tags: Clin Chim Acta Source Type: research
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