Early life epilepsies are a co-expression of developmental brain disorders

Early life epilepsies are series disorders frequently accompanied by a broad range of morbidities that include cognitive, behavioral, neuromuscular, and sleep disorders; enteric and other forms of autonomic dysfunction; sensory processing disorders; and other issues. Usually these morbidities cluster together in a single patient, multimorbidity. Rather than these being separate disorders, all, including the seizures, are manifestations or co-expressions of developmental brain disorders (DBD). Instead of viewing epilepsy as the disorder and the other features as comorbidities, approaching early life epilepsies as part of the spectrum of DBD could have implications for multidisciplinary care models, anticipatory guidance and counseling of parents, as well as the design of randomized trials and targeting important outcomes.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research