Sex differences in the prevalence of genetic mutations in FTD and ALS: A meta-analysis
Conclusions:
Higher female prevalence of C9orf72 hexanucleotide repeat expansions in ALS and GRN mutations in FTD suggest that sex-related risk factors might moderate C9orf72 and GRN-mediated phenotypic expression.
Source: Neurology - Category: Neurology Authors: Curtis, A. F., Masellis, M., Hsiung, G.-Y. R., Moineddin, R., Zhang, K., Au, B., Millett, G., Mackenzie, I., Rogaeva, E., Tierney, M. C. Tags: All Clinical Neurology, Amyotrophic lateral sclerosis, Frontotemporal dementia, Gene expression studies, All epidemiology VIEWS & amp;amp; REVIEWS Source Type: research
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