Decoration of trastuzumab with short oligonucleotides: synthesis and detailed characterization

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02216F, PaperAna Margarida Carvalho, Alex Manicardi, Cynthia Veliz Montes, Smita B Gunnoo, Rudolf J. Schneider, Annemieke Madder Trastuzumab (Herceptin[registered sign]) is an FDA-approved therapeutic antibody currently employed in the treatment of metastatic stages of breast cancer. Herein, we propose a simple, fast and cost-effective methodology to conjugate trastuzumab... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 9, 2017 Category: Molecular Biology Authors: Ana Margarida Carvalho Source Type: research