Effects of Aqueous Extracts of Palm Fruits (Elaeis guineensis) on Liver Function Indices of Male Wistar Albino Rats
This study investigated the effects of aqueous extracts of palm fruits on liver function indices of male Wistar albino rats with the view of understanding the hepatotoxic potentials of the extracts. Materials and Methods: Acute toxicity study was carried out with 18 male Wistar albino mice. Liver function indices were evaluated using 45 male Wistar albino rats and by following standard analytical protocols. The rats were divided into 5 groups with group 1 having 5 rats only and group 2-5 had 10 rats each. Group 1 rats were the normal control that received 2 mL kg1 b.wt., of normal saline. Five rats each from group 2-5 received 100, 200, 400 and 600 mg kg1 b.wt., of the fresh and fermented aqueous extracts of palm fruits, respectively for 28 days. Data was analyzed by one way ANOVA using SPSS. Results: The aqueous extracts were relatively safe as no death or adverse reactions were observed in the mice in 24 h after administration. There were significant (p0.05) when compared to the normal control. However, groups 4 and 5 that received higher doses of the fresh extract showed significant (p
A medial prefrontal cortex-nucleus acumens corticotropin-releasing factor circuitry for neuropathic pain-increased susceptibility to opioid reward, Published online: 21 May 2018; doi:10.1038/s41398-018-0152-4A medial prefrontal cortex-nucleus acumens corticotropin-releasing factor circuitry for neuropathic pain-increased susceptibility to opioid reward
We describe case reports from patients of the Occupational Disease Centre in Brest, France between 2013 and 2016. Consultations were conducted within the framework of clinical occupational medicine with a focus on real work situations. Diagnoses of workaholism were made according to Goodman's criteria. The situations of four patients are reported. Three of these suffered from workaholism: a 41-year-old sales representative, a 51-year-old nurse in progressive care and a 30-year-old saleswoman. The last case report concerns the situation of a 41-year-old team leader who was first suspected to have workaholism, but later diag...
Contributors : Heather Machkovech ; Arvind SubramaniamSeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Homo sapiensCellular stress is often accompanied by non-canonical initiation of translation at alternate start codons in mammalian cells. Here we systematically investigate the extent and impact of alternate translation initiation in the context of influenza virus infection. We use ribosome profiling with the initiation inhibitor lactidomycin to experimentally delineate translation initiation sites in a human lung epithelial cell line infected with influenza virus.
Another Nod From Nature Scientific ReportsPublications referencing use of our antibodies continue to build. We are recognized for having potentNeuropeptide Antibodies.This most recent publication references ourGuinea Pig Substance-P Antibody: Khaled Abdallah, Francis Nadeau, Francis Bergeron, Sylvie Blouin, V éronique Blais, Kelly M. Bradbury, Christine L. Lavoie, Jean-Luc Parent;, Louis Gendron. (2018). Adeno-associated virus 2/9 delivery of Cre recombinase in mouse primary afferents. Scientific Reports volume 8, Article number: 7321 (2018) doi:10.1038/s41598-018-25626-yFigure: Distribution of the Cre-GFP in t...
CONCLUSIONS: Currently, misconduct is the main cause of retraction. Specific strategies to limit this phenomenon must be implemented. It would be useful to standardize reasons and procedures for retraction. The development of a standard retraction form to be permanently indexed in a database might be relevant. PMID: 29776690 [PubMed - as supplied by publisher]
CONCLUSIONS: Overall, our findings could be used to clarify the appropriate health expenditure level or to obtain better environmental quality and social well-being. That is, empirical support is provided on how health management and policy makers should include more considerations for the use of cleaner fuels in developed countries. PMID: 29776689 [PubMed - as supplied by publisher]
The thumbnail take on finasteride has been that it prevents prostate cancer but increases the risk for high-grade disease. A new study debunks the latter idea.Medscape Medical News
CONCLUSIONS: The PHT has the potential to be substituted for manual interpretation of the HTT and to serve in a variety of clinical and research applications. PMID: 29775421 [PubMed - in process]
John Stuart Mill was born. A revolutionary thinker, Mill's ideas had a profound influence on the history and development of psychology. A notable example being Mill's empirically driven system of inductive logic, which was adopted and applied by Wilhelm Wundt, a founding figure of modern psychology. Mill also created a lasting legacy within psychology through his notion of mental chemistry, namely his suggestion that a complex idea is greater than the sum of its parts and constitutes more than just a collection of simple ideas added together. This doctrine of association became a key tenet of Gestalt psychology. See follow...
Smart technologies can sift through data to help the NHS spot diseases quicker, the PM is to say.