What Medications Should Be Avoided with Long QT Syndrome?

Discussion Mycoplasma pneumoniae is a frequent cause of pharyngitis, pneumonia and acute bronchitis, but acute otitis media is uncommon. Symptoms are usually self-limited and variable and include cough (non-productive usually but later can be productive), fever, fatigue and occasionally headache. Coryza is rare. Cough can continue for 3 to 4 weeks and can be accompanied by wheezing. Radiographic changes include diffuse infiltrates or focal abnormalities but are variable. Long QT syndrome (LQTS) is a group of disorders that have a prolonged QT interval and a polymorphic ventricular tachycardia. Torsade de pointes (“twisting of the points”) is a particular type of polymorphic ventricular tachycardia that can be associated with LQTS. LQTS can be congenital or acquired. It is increasingly being recognized and may be as common as 1:2500. Congenital LQTS has many different types. It is associated with chromosomal changes which cause myocardial ion channel problems which interferes with normal cardiac polarization-repolarization leading to arrhythmias. LQT1 accounts for 30-35% of LQTS. LQT2 accounts for 25-40%. LQT3 accounts for 5-10% of patients, and the others account for the remaining percentages. Phenotypically there are two main clinical phenotypes. Romano-Ward syndrome is an autosomal dominant trait that has LQTS without sensorineural deafness. Jervell and Land-Nielsen syndrome is an autosomal recessive trait that has LQTS with bilateral sensorineural deafness. ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news