Vital Signs: Trends in Incidence of Cancers Associated with Overweight and Obesity - United States, 2005-2014.

CONCLUSIONS: The burden of overweight- and obesity-related cancer is high in the United States. Incidence rates of overweight- and obesity-related cancers except colorectal cancer have increased in some age groups and states. IMPLICATIONS FOR PUBLIC HEALTH PRACTICE: The burden of overweight- and obesity-related cancers might be reduced through efforts to prevent and control overweight and obesity. Comprehensive cancer control strategies, including use of evidence-based interventions to promote healthy weight, could help decrease the incidence of these cancers in the United States. PMID: 28981482 [PubMed - in process]
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research

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This study aims to reflect on the process of adoption of the preprints publication model, briefly delimiting its history and current use by the national and the international scientific community. Departing from the literature and a consultation of preprint repositories, this reflection intends to highlight the main challenges that preprint implementation will face in the Nursing area, along with its specificities. While considering its benefits for scientific dissemination, this study points out the difficulties that may arise from the implementation of mostly north-American science models in a peripheral country such as ...
Source: Revista da Escola de Enfermagem da USP - Category: Nursing Source Type: research
Ceribell Inc., the company that set out to simplify bedside electroencephalogram (EEG) monitoring with its Ceribell Rapid Response EEG and took home the 2019 Medical Design Excellence Awards Best-in-Show award, has just launched Clarity, a new 24/7 bedside EEG monitoring and alerting technology. The company made the announcement at the American Epileptology Society Annual Meeting. Ceribell Rapid Response EEG was designed to ease EEG setup and triage for patients with suspicion of seizure, and application does not require an EEG technician. In addition to winning the MDEA Best in Show, the system was also recognized with a ...
Source: MDDI - Category: Medical Devices Authors: Tags: Software Source Type: news
Among women with metastatic breast cancer, use of an investigational oral form of paclitaxel yielded a higher overall response rate than the IV form, but administration was unique and time-consuming.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Jack Cuzick, Ivana Sestak, John F Forbes, Mitch Dowsett, Simon Cawthorn, Robert E Mansel, Sibylle Loibl, Bernardo Bonanni, D Gareth Evans, Anthony Howell, IBIS-II investigatorsSummaryBackgroundTwo large clinical trials have shown a reduced rate of breast cancer development in high-risk women in the initial 5 years of follow-up after use of aromatase inhibitors (MAP.3 and International Breast Cancer Intervention Study II [IBIS-II]). Here, we report blinded long-term follow-up results for the IBIS-II trial, which compared anastrozole with placebo...
Source: The Lancet - Category: General Medicine Source Type: research
ConclusionsThis study provides initial perspectives on measles preparedness among Idaho CAHs, despite limited generalizability. Future studies should explore whether self-reported preparedness measures reflect the ability of the CAHs to control measles spread when cases present for care.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
ConclusionsMHSCC seems to show a better overall survival compared to OSCC of other locations and is less likely to develop regional and distant metastasis; END might not be necessary in early stage tumors.
Source: Journal of Cranio Maxillofacial Surgery - Category: ENT & OMF Source Type: research
ConclusionThe close relationship between HPV and oropharyngeal squamous cell carcinoma could not be shown in larynx malignancy in many studies, including our study. Our findings support a limited role of HPV in laryngeal carcinogenesis. Protein16 is not a reliable surrogate for HPV status in laryngeal cancers and is not a predictor of laryngeal cancer survival. Supraglottic localization of tumor was determined to be increased in protein16 positive cases. The correlation between protein16 positivity and supraglottic area location was determined to be statistically significant. There is a need for more populated clinical tri...
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
Source: Journal of Pediatric Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Seid Hamzic, Dominic Kummer, Tanja K. Froehlich, Markus Joerger, Stefan Aebi, Claire Palles, Ian Thomlinson, Didier Meulendijks, Jan H.M. Schellens, Xandra García-González, Luis A. López-Fernández, Ursula Amstutz, Carlo R. LargiadèrAbstractTo assess the proposed associations of the c.742-227G > A (rs2612091) polymorphism within the Enolase Superfamily Member 1 gene (ENOSF1) and two variants in the adjacent Thymidylate Synthase gene (TYMS): the 5’VNTR 28bp-repeat (rs45445694...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Qianqian Liu, Jiao Qu, Mingxia Zhao, Qiang Xu, Yang SunAbstractSrc homology 2 (SH2)-containing protein tyrosine phosphatase 2 (SHP2) is a major phosphatase involved in several cellular processes. In recent years, SHP2 has been the focus of significant attention in human diseases, particular in cancer. Several studies have shown that SHP2 plays an important role in regulating immune cell functions in tumor microenvironment. A few clinical trials conducted using SHP2 allosteric inhibitors have shown remarkable anti-tumor benefits an...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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