Stimulation of Anxiety-Like Behavior via ERK Pathway by Competitive Serotonin Receptors 2A and 1A in Post-Traumatic Stress Disordered Mice.

CONCLUSION: These findings suggest competive interaction between 5HT2AR and 5HT1AR actively affects anxiety-like behavior in the hippocampi of PTSD mice via the ERK pathway. PMID: 28977803 [PubMed - as supplied by publisher]
Source: Neuro-Signals - Category: Neurology Authors: Tags: Neurosignals Source Type: research

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This week’s Psychology Around the Net explores how anxiety looks in children, how managers can work with employees dealing with depression, why young girls are struggling more with mental health issues than their male counterparts, a new bill that would make mental health a priority for first responders, and more.     Anxiety is Different for Kids: Do you have a child who struggles with anxiety? Would you even recognize it? According to the author, anxiety disorders in children can manifest in a variety of ways, and kids typically don’t display symptoms in the same way that adults do. Michigan-based ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic Children and Teens Depression Disorders General Mental Health and Wellness Psychology Psychology Around the Net Research Students Trauma Childhood Anxiety Childhood Trauma First Responders girls' mental health Source Type: blogs
In this study, we used probabilistic tractography to examine BNST-insula structural connectivity in humans. We used two methods of dividing the insula: 1) anterior and posterior insula, to be consistent with much of the existing insula literature; and 2) eight subregions that represent informative cytoarchitectural divisions. We found evidence of a BNST-insula structural connection in humans, with the strongest BNST connectivity localized to the anteroventral insula, a region of agranular cortex. BNST-insula connectivity differed by hemisphere and was moderated by sex. These results translate rodent findings to humans and ...
Source: NeuroImage - Category: Neuroscience Source Type: research
Authors: Petrowski K, Wichmann S, Pyrc J, Steudte-Schmiedgen S, Kirschbaum C Abstract The role of cortisol as a premorbid vulnerability factor for trauma sequelae remains unclear. Furthermore, the onset of long-term endocrine changes in response to first time trauma as a function of later psychopathology is not clarified yet. Thus the predictive value of pre- and post-traumatic hair cortisol concentrations (HCC) for psychological trauma sequelae was investigated in response to motor vehicle crash (MVC).A total of N = 62 MVC survivors participated in this study [46 females, mean age (SD): 43.94(12.95)]...
Source: Stress - Category: Research Tags: Stress Source Type: research
Conclusions: Offering opportunities such as family care rituals for family members to be involved with providing care for family members in the ICU was associated with reduced symptoms of post-traumatic stress disorder. This intervention may lessen the burden of stress-related symptoms in family members of ICU patients.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research
It’s completely normal to feel anxious in social situations. Be it giving a speech or talking on the phone, social anxiety affects a surprisingly large percentage of the population. However, when one experiences considerable distress and an impaired ability to function in parts of their daily life, it is likely they will be diagnosed as social anxiety disorder.1 Many people with social anxiety disorder do not know that they have it. They may recognize that there is something “wrong,” but do not know what it is or what to do about it. This is where mindfulness can help. By being mindful, aware of the prese...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic Mindfulness Jon Kabat Zinn Meditation secular mindfulness Social Anxiety Source Type: blogs
BOSTON (CBS) – It’s estimated that one in four pregnancies ends in miscarriage, and a new study published in the American Journal of Obstetrics and Gynecology finds that many of those women suffer long-term psychological distress. Researchers in London and Belgium looked at more than 650 women who had experienced early loss, either from miscarriage before 12 weeks or from an ectopic pregnancy, where the embryo grows outside of the uterus. One month later, they found that almost a third of women suffered post-traumatic stress, one in four experienced moderate-to-severe anxiety and about 10-percent had moderate-t...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Healthwatch Syndicated CBSN Boston Syndicated Local Dr. Mallika Marshall Miscarriage Source Type: news
A study by Imperial College London fround 18 per cent of women said nine months after the loss they still relive it through nightmares and are plagued with anxiety, depression and guilt.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Around one in six women who experience early pregnancy loss have symptoms of post-traumatic stress disorder, anxiety or depression nine months later
Source: New Scientist - Health - Category: Consumer Health News Source Type: research
Posttraumatic stress disorder (PTSD) can develop after exposure to severe psychological trauma, leaving patients with disabling anxiety, nightmares, and flashbacks. Current treatments are only partially effective, and development of better treatments is hampered by limited knowledge of molecular mechanisms underlying PTSD. We have discovered that the glucocorticoid receptor (GR) and FK506 binding protein 51 (FKBP51) form a protein complex that is elevated in PTSD patients compared with unaffected control subjects, subjects exposed to trauma without PTSD, and patients with major depressive disorder (MDD). The GR-FKBP51 comp...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Studies show a relationship between some mental illnesses and suicides and different environmental variables such as air pollution, characterized by stress at the neuropsychological level. Despite the fact that traffic noise is also a powerful neurological...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
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