Polycomb silencing mediated by specific DNA-binding recruiters

Nature Genetics 49, 1416 (2017).
doi:10.1038/ng.3961

Authors: Eduardo March & Sara Farrona
Regulation of epigenetic factors through their recruitment to specific genomic regions is still poorly understood. A recent study demonstrates a global mechanism of tethering Polycomb group (PcG) proteins through sequence-specific DNA-binding factors.

Source: Nature Genetics - September 27, 2017 Category: Genetics & Stem Cells Authors: Eduardo March Sara Farrona Tags: News and Views Source Type: research