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Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups

AbstractObjectiveTo investigate the potential alleviating effects of acupuncture on maternal separation (MS)-induced changes in plasma pro-inflammatory cytokine levels of rat pups.MethodsOn postnatal day 15, rat pups were randomly assigned to 4 groups (n=6 per group) using a random number table: normal, MS, MS with acupuncture stimulation at Shenmen (HT 7) acupoint (MS+HT 7), and MS with acupuncture stimulation at Chengshan (BL 57) acupoint (MS+BL 57) groups. Rat pups in the normal group were housed with their mothers under standard conditions; those in the MS, MS+HT 7 and MS+BL 57 groups were maternally separated and individually maintained. Acupuncture stimulation was performed at HT 7 or BL 57 acupoints once a day for 7 consecutive days. A tail suspension test was performed to measure immobility time of rats and the plasma was collected on postnatal day 21, then levels of corticosterone (CORT), interleukin (IL)-1 β, IL-6 and glial cell-derived neurotrophic factor (GDNF) in plasma were measured.ResultsCompared with the normal group, the immobility time and the plasma levels of CORT, IL-1 β, IL-6 and GDNF in the MS group were significantly increased (P
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research

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Abstract: Biological and environmental changes to maternal and newborn microbiomes in the postnatal period can affect health outcomes for the mother–baby dyad. Postpartum sleep deprivation and unmet dietary needs can alter commensal bacteria within the body and disrupt gut-brain communication. Perineal injury and breast infections also change microbial community composition, potentiating an environment favoring pathogen growth. The gut microbiome refers to the collection of microorganisms working in harmony. Disruptions within the gut microbiome and gut-brain communication may lead to postpartum depression, a potenti...
Source: MCN: The American Journal of Maternal Child Nursing - Category: Nursing Tags: Feature Source Type: research
Purpose: The purpose of this study was to summarize birth mothers' descriptions of unplanned pregnancy experienced in their twenties and how open adoption influenced their lives. Study Design and Methods: Naturalistic inquiry was used with purposive sampling from one agency and telephone interviews of women who experienced unplanned pregnancy in their twenties and relinquishment through open adoption. Recorded, transcribed, and deidentified interviews were analyzed for qualitative themes. Results: Fifteen participants judiciously weighed the open adoption decision. Over half parented other children prior to placement. Mo...
Source: MCN: The American Journal of Maternal Child Nursing - Category: Nursing Tags: Feature Source Type: research
Publication date: Available online 20 October 2017 Source:Physiology & Behavior Author(s): Ehtramolsadat Sahafi, Maghsoud Peeri, Mir-Jamal Hosseini, Mohammad Ali Azarbyjani Early life stress (ELS) is known as a risk factor for the development of depression and its associated comorbidities, such as cardiomyopathy in depressed patients. Mitochondrial dysfunction plays a critical role in the pathophysiology of depression and cardiovascular diseases. Evidence indicates that regular physical activity has therapeutic effects on both mood and cardiovascular disorders. Therefore, the voluntary running wheel exercise (RW) duri...
Source: Physiology and Behavior - Category: Physiology Source Type: research
In this study, we investigated the association between mode of delivery at first childbirth and birth experience, using a new scale developed specifically to measure women's affective response. MethodsThis was a prospective cohort study of 3006 women who were interviewed during pregnancy and 1ÔÇÉmonth postpartum. The First Baby Study Birth Experience Scale was used to measure the association between mode of delivery and women's postpartum feelings about their childbirth, taking into account relevant confounders, including maternal age, race, education, pregnancy intendedness, depression, social support, and maternal and ne...
Source: Birth - Category: OBGYN Authors: Tags: ORIGINAL ARTICLE Source Type: research
Authors: Zhang XL, Wang L, Xiong L, Huang FH, Xue H Abstract The aim of this study was to investigate the antidepressive effects of timosaponin B-III (TB-III) and the underlying mechanism. A postpartum depression (PPD) mouse model was established by the administration of dexamethasone sodium phosphate during pregnancy. Mice with PPD were assigned to the following groups: Model, fluoxetine and high, medium and low doses of TB-III. Post-parturient mice without PPD served as a normal control group. To examine the effect of TB-III, mice were treated with TB-III, then forced swimming tests (FSTs) and tail suspension tes...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
We are honored to be the winner of the 2017 WEGO Health Award in the Best in Show: Podcast category for our outstanding weekly podcast, The Psych Central Show, hosted by Gabe Howard and Vincent M. Wales. We are humbled by this achievement for our podcast, which offers a candid chat on mental health and psychology topics. Congratulations to Gabe &Vincent for doing such excellent work each and every week! Each week, Gabe and Vincent tackle a different issue surrounding mental illness and mental health in society. Sometimes they have guests (and in today’s episode, they even interview me talking about the psycholo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Mental Health and Wellness Policy and Advocacy podcast award wego award wego health Source Type: blogs
Abstract Objectives: to verify associations between maternal depressive symptoms with child malnutrition or child excess weight. Methods: prospective study with data from the BRISA prenatal cohort in S ão Luís, Brazil, obtained from the 22nd to the 25th week of gestation (in 2009 and 2010) and, later, when children were aged 12 to 32 months (in 2010 and 2012). Maternal depressive symptoms were identified using the Center for Epidemiologic Studies Depression Scale (CES-D) and the Edinburgh Postna tal Depression Scale (EPDS). For the excess weight evaluation, BMI z-score for age> +2 was used. For measuring c...
Source: Revista Brasileira de Saude Materno Infantil - Category: Midwifery Source Type: research
Women at risk of depression while pregnant or after giving birth could benefit from increasing their intake of probiotics during pregnancy, according to a New Zealand study.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
CONCLUSIONS: There are insufficient RCT data to evaluate the use of oral anti-diabetic agents in women with established diabetes, impaired glucose tolerance or previous gestational diabetes who are planning a pregnancy, or in pregnant women with pre-existing diabetes. Low to very low-quality evidence suggests possible reductions in pregnancy-induced hypertension, caesarean section birth and neonatal hypoglycaemia with metformin compared with insulin for women with type 2 diabetes diagnosed before or during their pregnancy, and no clear differences in pre-eclampsia, induction of labour and babies that are large-for-gestatio...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
A new iPhone app launched for free by Massachusetts General Hospital (MGH) looks not only to bring convenient postpartum depression (PPD) screening to more expecting and postpartum women, but also looks to redefine the gold standard for post-partum depression diagnosis.
Source: mobihealthnews - Category: Information Technology Source Type: news
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