Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups

AbstractObjectiveTo investigate the potential alleviating effects of acupuncture on maternal separation (MS)-induced changes in plasma pro-inflammatory cytokine levels of rat pups.MethodsOn postnatal day 15, rat pups were randomly assigned to 4 groups (n=6 per group) using a random number table: normal, MS, MS with acupuncture stimulation at Shenmen (HT 7) acupoint (MS+HT 7), and MS with acupuncture stimulation at Chengshan (BL 57) acupoint (MS+BL 57) groups. Rat pups in the normal group were housed with their mothers under standard conditions; those in the MS, MS+HT 7 and MS+BL 57 groups were maternally separated and individually maintained. Acupuncture stimulation was performed at HT 7 or BL 57 acupoints once a day for 7 consecutive days. A tail suspension test was performed to measure immobility time of rats and the plasma was collected on postnatal day 21, then levels of corticosterone (CORT), interleukin (IL)-1 β, IL-6 and glial cell-derived neurotrophic factor (GDNF) in plasma were measured.ResultsCompared with the normal group, the immobility time and the plasma levels of CORT, IL-1 β, IL-6 and GDNF in the MS group were significantly increased (P
Source: Chinese Journal of Integrative Medicine - Category: Internal Medicine Source Type: research

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Publication date: April–June 2018Source: Journal of Ayurveda and Integrative Medicine, Volume 9, Issue 2, Supplement 1Author(s): K. Vandana Vasudevan, Hemavathi, Anjali
Source: Journal of Ayurveda and Integrative Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 17 July 2018Source: NeuroscienceAuthor(s): Gudrun Winther, Betina Elfving, Heidi Kaastrup Müller, Sten Lund, Gregers WegenerAbstractPrenatal exposure to high-fat diet (HFD) might predispose offspring to develop metabolic and mental disorders later in life. Insight into the molecular and behavioural consequences of maternal HFD on offspring is sparse but may involve both neuroinflammation and a dysregulated neuroendocrine stress axis. Thus, the aim of this work was to: i) investigate the influence of maternal HFD on memory, anxiety and depression-like behaviour in adult offspring and ...
Source: Neuroscience - Category: Neuroscience Source Type: research
In clinical studies, depression in pregnancy (antenatal depression) has been recognized as a key clinical risk factor for the transmission of abnormal mental health and behavior to the offspring generation, over and above the effects of disrupted maternal care due to postnatal depression (Davis et al., 2007; Pawlby et al., 2009; Gerardin et al., 2010; Hay et al., 2010; Pearson et al., 2013; Van Batenburg-Eddes et al., 2013). These effects of antenatal depression are wide-ranging, and include adverse effects on neonatal behavior (Zuckerman et al., 1990; Field et al., 2004a; Diego et al., 2005; Goodman et al., 2011; Pacheco ...
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research
July 17, 2018When hospitals or clinics are attacked, women often become targets. But what do we know about the real impact on their health and well-being?In April 2017, 60 militia members attacked a hospital in Cinq, a city in the Kasai district of the Democratic Republic of Congo. The rebels set fire to a surgical suite, trapping 35 patients inside, and then torched most of the hospital. They sexually assaulted women and girls with sticks and firearms, including a woman who had just given birth hours before.The details of this attack are horrifying. More than 100 people died, including 90 patients and two health workers.B...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Source Type: news
BACKGROUND: Mental illness in women leads to an increased maternal morbidity and mortality. Postpartum depression accommodates various groups of depressive disorders and syndromes that occur within the first immediate year after delivery. Thus, this study ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Violence and Weapons Issues Source Type: news
AbstractObjectives The Edinburgh Postnatal Depression Scale (EPDS) identifies women with depressive symptoms in pregnancy. Our primary objective was to determine the prevalence of EPDS screen-positive women delivering on our no prenatal care (laborist) service and to compare these patients to private patients delivering with prenatal care.Methods Retrospective cohort analysis of EPDS scores during January 1, 2015 to June 18, 2015  was conducted. Scores ≥ 10 were considered at-risk. Results were analyzed as an aggregate and then as no prenatal care versus prenatal care. Characteristics for patients wit...
Source: Maternal and Child Health Journal - Category: Health Management Source Type: research
Parental psychiatric symptoms may negatively affect the outcome of children ’s psychopathology. Studies have so far mainly showed a negative effect of maternal depression. We studied the associations between a broad range of psychiatric symptoms in mothers as well as fathers with child’s outcome.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: New Research Source Type: research
Antepartum depression is a common and high impact disease, with major impact on both maternal and fetal health, as well as infant development (Steegers et al., 2016; Woody et al., 2017). Women who suffer from antepartum depression are more likely to experience postpartum depression as well (Milgrom et al., 2008). Children who are exposed to maternal depression during pregnancy have a higher risk of adverse birth outcomes, such as prematurity and being small for gestational age, and more often show cognitive, emotional and behavioural problems in childhood, adolescence and adulthood (Grote et al., 2010; Jarde et al., 2016; Talge et al., 2007).
Source: Psychiatry Research - Category: Psychiatry Authors: Source Type: research
Perinatal depression is an important contributor to maternal morbidity and mortality worldwide. Migrant women, particularly those resettling within low- and middle-income settings, are at increased risk of per...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
Conclusion: Postpartum depression is a common mental health problem during the postnatal period. Domestic violence was positively and significantly associated with the symptom of postpartum depression. Maternity services shall consider a sector that provides health care for women who encounter violence and develop symptoms of postpartum depression. PMID: 29997678 [PubMed]
Source: Clinical Practice and Epidemiology in Mental Health - Category: Psychiatry Tags: Clin Pract Epidemiol Ment Health Source Type: research
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