Increased galectin-3 levels are associated with abdominal aortic aneurysm progression and inhibition of galectin-3 decrease elastase-induced AAA development.

In conclusion, increased galectin-3 levels are associated with AAA progression, while galectin-3 inhibition decreased experimental AAA development. Our data suggest the potential role of galectin-3 as a therapeutic target in AAA.

Source: Clinical Science - October 5, 2017 Category: Biomedical Science Authors: Fernandez-Garcia, C.-E., Tarin, C., Roldan-Montero, R., Martinez-Lopez, D., Torres-Fonseca, M., Lindhot, J. S., Vega de Ceniga, M., Egido, J., Lopez de Andres, N., Blanco-Colio, L.-M., Martin-Ventura, J.-L. Tags: PublishAheadOfPrint Source Type: research