Clinical Characteristics of Pruritus and Pain in Patients with Hidradenitis Suppurativa.

This study evaluated pruritus and pain among 103 patients with HS. Pruritus and pain intensity were assessed with a visual analogue scale, numerical rating scale and 4-item Itch Questionnaire. Dermatology Life Quality Index (DLQI) was implemented to assess quality of life (QoL) issues. Various clinical features and factors influencing pruritus were also examined. Pruritus and pain during the last week were reported among 41.7% and 77.5% of patients, respectively. The presence of pruritus did not have an impact on QoL (DLQI), nor did it show interaction with the pain in this regard. The presence of pain was a crucial contributor, even more relevant than disease severity. Nonetheless, intensity of pruritus correlated with DLQI. The most troublesome symptom of HS was pain, followed by exudation, pruritus, appearance and smell, consecutively. Pruritus of mild-to-moderate intensity is a common HS-associated symptom that adversely affects patients’ QoL. PMID: 28971209 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research

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In conclusion, enchondroma growth was a rare event and typically occurred at two years follow-up in our series. Given the low risk for malignant transformation, we propose surveillance with plain radiographic follow-up for stable enchondromas every 3-6 months for the first year and then annually for at least three years of total follow-up. The most significant costs savings can be made by limiting MRI imaging in the absence of clinical or radiographic concern. Additional studies are needed to determine the long-term risk of growth or declaration of chondrosarcoma.Level of Evidence: IV. PMID: 31413693 [PubMed - in process]
Source: Iowa orthopaedic journal - Category: Orthopaedics Tags: Iowa Orthop J Source Type: research
Conclusions: Our study suggests CT may be adequate to rule out hip and pelvic fractures in this patient population. CT may be preferable to MRI based on decreased time spent in the ED and the large percentage of elderly patients with contraindications to MRI.Level of Evidence: III. PMID: 31413692 [PubMed - in process]
Source: Iowa orthopaedic journal - Category: Orthopaedics Tags: Iowa Orthop J Source Type: research
Conclusions: Every child who presents with atypical scoliosis should have a complete physical examination and appropriate imaging studies seeking an underlying cause.Level of Evidence: V. PMID: 31413680 [PubMed - in process]
Source: Iowa orthopaedic journal - Category: Orthopaedics Tags: Iowa Orthop J Source Type: research
Conclusions: A comparison of pre- and post-operative lateral radiographs showed 27° segmental lordosis correction, and intra-operative fluoroscopy showed correlation between extension of the table and segmental lordosis correction. Bilateral facetectomy and TLIF allows for segmental lordosis correction. Use of the hinged table allowed for ideal positioning during the decompression and controlled osteotomy closure with close correlation between table position and segmental alignment.Level of Evidence: V. PMID: 31413679 [PubMed - in process]
Source: Iowa orthopaedic journal - Category: Orthopaedics Tags: Iowa Orthop J Source Type: research
ec GB Abstract BACKGROUND: Pain is a prominent symptom of Hidradenitis suppurativa (HS) and has been defined as a domain in the Core Outcome Set for the disease. In addition, quality and intensity of pain is influenced by depression and anxiety both of which are associated with HS. OBJECTIVES: To describe HS-related pain quantitatively as well as qualitatively. Secondarily to investigate how disease severity, depression and anxiety correlate with self-reported pain qualities. METHODS: Pain perception was investigated using McGill Pain Questionnaire (MPQ). Symptoms of depression and anxiety were examined ...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Abstract There is a lack of data evaluating the influence of hidradenitis suppurativa-related subjective symptoms on sleep quality. The aim of this study was to assess the influence of itch and pain on sleep quality in 108 patients with hidradenitis suppurativa compared with 50 controls. The Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate a spectrum of sleep disturbances. Mean ± standard deviation AIS and PSQI scores among patients with hidradenitis suppurativa vs. controls were assessed as 5.4 ± 4.3 vs. 5.5 ± 3.4 a...
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 214. Question 1 Who first described the phenomenon of malignant hyperthermia? + Reveal the Funtabulous Answer expand(document.getElementById('ddet945038639'));expand(document.getElementById('ddetlink945038639')) Michael Denborough Question 2 Fox&rs...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five apocrine miliaria Charles Maitland fox sign george henry fox john addison fordyce jones fracture malignant hyperthermia michael denborough Newgate pimp Robert Jones smallpox william osler Source Type: blogs
AbstractBackgroundPruritus is still a forgotten aspect of hidradenitis suppurativa (HS) and, to date, has never been adequately studied.ObjectiveThe aim of this study was to determine the prevalence, and explore the characteristics, of pruritus in a well-defined cohort of HS patients.SettingAn academic hospital-based cross-sectional study in The Netherlands.MethodsA numerical rating scale (NRS, 0 –10) was used to determine the prevalence of HS-related itch (NRS score ≥3). Candidate predictors for pruritus were subsequently determined using logistic regression models, and the impact of pruritus was assessed using a...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
Abstract Hidradenitis suppurativa/acne inversa (HS) is a chronic inflammatory skin disease characterized by painful, recurrent nodules and abscesses that rupture and lead to sinus tracts and scarring. To date, an evidence-based therapeutic approach has not been the standard of care and this is likely due to the lack of evidence based treatment guidelines. The purpose of this study was to promote a holistic evidence-based approach which implemented Level of Evidence and Strength of Recommendation for the treatment of HS. Based upon the European Dermatology Forumguidelines for the management of HS, evidence-based ap...
Source: ENDOCR REV - Category: Endocrinology Authors: Tags: Rev Endocr Metab Disord Source Type: research
Abstract Hidradenitis suppurativa/acne inversa (HS) is a chronic inflammatory skin disease characterized by painful, recurrent nodules and abscesses that rupture and lead to sinus tracts and scarring. To date, an evidence-based therapeutic approach has not been the standard of care and this is likely due to the lack of evidence based treatment guidelines. The purpose of this study was to promote a holistic evidence-based approach which implemented Level of Evidence and Strength of Recommendation for the treatment of HS. Based upon the European Dermatology Forumguidelines for the management of HS, evidence-based ap...
Source: Reviews in Endocrine and Metabolic Disorders - Category: Endocrinology Source Type: research
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