Diversity-driven and facile 1,3-dipolar cycloaddition to access dispirooxindole-imidazolidine scaffolds

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02319G, CommunicationYu-lun Qian, Peng-Ju Xia, Jun Li, Qinglan Zhao, Jun-An Xiao, Haoyue Xiang, Hua Yang Diversity-driven three-component 1,3-dipolar cycloaddition of isatin, amino acid and isatin-derived ketimine was developed to facilely assemble dispirooxindole-imidazolidine skeletons bearing vicinal quaternary carbon centers. This protocol features additive-free, minimal solvent usage... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 5, 2017 Category: Molecular Biology Authors: Yu-lun Qian Source Type: research