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Fluid Resuscitation in Pediatric Septic Shock: The Case Against Haste*

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Source: Pediatric Critical Care Medicine - Category: Pediatrics Tags: Editorials Source Type: research

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CONCLUSION: Data from 34 large studies on 498,146 septic adult patients clearly showed a prevalence of males despite the expected female predominance. Further studies are required to explain the reasons, to evaluate if a difference is present in survival rate, and to identify gender-tailored preventive measures and treatments. PMID: 29239150 [PubMed - as supplied by publisher]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
We present a case of 13 year old male, presented with hypoactivity and inability to bare his own weight, developed septic shock due to pneumococcus with Acute Respiratory Distress Syndrome, and was found to have neurological findings of Guillain-Barre Syndrome. A new association in pediatric age group, never been reported before.
Source: IDCases - Category: Infectious Diseases Source Type: research
CONCLUSION Based on our experience with this particular case, we could safely conclude that an operation for cholecystocolonic fistula presence in the setting of biliary obstruction that failed decompressive attempts should be performed in an urgent fashion to avoid biliary sepsis development.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Key Clinical Message A 44‐year‐old immunocompetent man with gastroenteritis received supportive care and empiric antibiotics. After an initial response, he developed septic shock. Blood cultures grew Gram‐positive bacilli with antibiotic adjustment. However, he succumbed within 36 h. After the patient's death, Listeria monocytogenes was identified on blood culture. A 44‐year‐old immunocompetent man with gastroenteritis received supportive care and empiric antibiotics. After an initial response, he developed septic shock. Blood cultures grew Gram‐positive bacilli with antibiotic adjustment. However, he suc...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: Case Report Source Type: research
Authors: Wang DW, Yin YM, Yao YM Abstract The vagus nerve can sense peripheral inflammation and transmit action potentials from the periphery to the brainstem. Vagal afferent signaling is integrated in the brainstem, and efferent vagus nerves carry outbound signals that terminate in spleen and other organs. Stimulation of efferent vagus nerve leads to the release of acetylcholine in these organs. In turn, acetylcholine interacts with members of the nicotinic acetylcholine receptor (nAChR) family, particularly with the alpha7 nicotinic acetylcholine receptor (α7nAChR), which is expressed by macrophages and oth...
Source: International Reviews of Immunology - Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research
We appreciate the comments from Dr. Jha. According to the study protocol, all patients received a cardiac output monitor aiming to optimize fluid status and cardiac index. Therefore, as our data show, with norepinephrine or vasopressin, we did not observe either a reduction in the cardiac index or a worsening of tissue perfusion and oxygenation parameters as lactate and central venous oxygen saturation.1 Furthermore, the incidence of low cardiac output and cardiogenic shock in the norepinephrine and vasopressin groups was not different. We attribute this to the fact that we assessed the fluid status and used inotropes regu...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Conditions:   Septic Shock;   Sepsis;   Pathologic Processes;   Shock;   Infection;   Systemic Inflammatory Response Syndrome;   Inflammation Interventions:   Biological: Allogeneic Bone Marrow-Derived Human Mesenchymal Stem Cells;   Other: Placebo Sponsors:   Ottawa Hospital Research Institute;   Canadian Institutes of Health Research (CIHR);   Ontario Institute for Regenerative Medicine (OIRM);   Stem Cell Network Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsA case of internal hernia formation is quite rare; accurate preoperative diagnosis and timely surgery are essential because it can cause strangulation of the ileus. However, the incidence of this internal herniation is low and preoperative diagnosis is difficult. An accurate preoperative diagnosis of internal hernia is still a challenge.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Abstract Capnocytophaga canimorsus is a Gram-negative bacterium present in the oral cavities of cats and dogs. It is known for its capability to cause life-threatening sepsis following a dog bite, especially in immunocompromised patients. We report the case of a 67-year-old man who suffered from septic shock and multiorgan failure presumably following contamination of a pre-existing minor skin lesion by canine saliva. The purpose of this report is to raise awareness of Capnocytophaga canimorsus among physicians when faced with a patient presenting with fulminant septic shock and Gram-negat...
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
Conclusion: This study identified several risk factors associated with blood stream infections caused by Candida over 10-years period. Continuous surveillance programs to monitor such types of infection are of great value to antimicrobial stewardship programs.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research
More News: Pediatrics | Septic Shock