Coordination, redox properties and SOD activity of Cu(II) complexes of multihistidine peptides.

Coordination, redox properties and SOD activity of Cu(II) complexes of multihistidine peptides. J Inorg Biochem. 2017 Sep 30;177:198-210 Authors: Csire G, Timári S, Asztalos J, Király JM, Kiss M, Várnagy K Abstract The results of electrochemical and SOD activity measurements of such copper(II) complexes of terminally protected multihistidine peptides that may mimic the active site of CuZnSOD enzyme are submitted and completed with solution equilibrium studies of some copper(II)-ligand systems. The equilibrium data confirm that the thermodynamic stabilities increase with the increasing number of histidyl residues in the amino acid sequence, the stability order, however, can be finely tuned by the number and quality of amino acids between histidine residues. Based on the cyclic voltammetric studies we concluded that the formal reduction potential values of imidazole nitrogen coordinated complexes decrease with the increasing number of imidazole donor atoms in the coordination sphere. However, the redox parameters of [CuH-1L](+) and [CuH-2L] complexes containing amide nitrogen coordination can be determined as well. All formal potential values of [CuL](2+), [CuH-1L](+) and [CuH-2L] complexes fall in the middle potential range of SOD activity. Finally, after the detailed analysis of species distribution curves based upon the equilibrium data SOD activity of copper(II) containing systems at two pH (pH=6.8 and 7.4) were determined. The imi...
Source: Journal of Inorganic Biochemistry - Category: Biochemistry Authors: Tags: J Inorg Biochem Source Type: research

Related Links:

CONCLUSIONS: Lymphoma represents a significant burden that can be reduced with the implementation of improved diagnosis and treatment methods, which must be taken into account in resource allocation and management policies. PMID: 32450710 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
Publication date: Available online 26 May 2020Source: Nitric OxideAuthor(s): Weili Wang, Liang Hu, Shimin Chang, Linsha Ma, Xiangchun Li, Zi Yang, Conglin Du, Xingmin Qu, Chunmei Zhang, Songlin Wang
Source: Nitric Oxide - Category: Chemistry Source Type: research
Publication date: Available online 27 May 2020Source: Journal of Industrial and Engineering ChemistryAuthor(s): Eun Jin Jeong, Eunmi Im, Dong Choon Hyun, Jung Woo Lee, Geon Dae Moon
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 27 May 2020Source: Journal of Industrial and Engineering ChemistryAuthor(s): Nian Hong, Qin Cheng, Ashantha Goonetilleke, Erick R. Bandala, An Liu
Source: Journal of Industrial and Engineering Chemistry - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): C. Dhanraj, K. Ravichandran, P. Kavitha, P.K. Praseetha
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): J. Camarillo-Cisneros, C. Arzola-Álvarez, R.M. Cabral-Lares, C. Arzate-Quintana, A. Arzola-Rubio
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): Ali Allahresani, Mehri Mohammadpour Sangani, Mohammad Ali Nasseri, Kaveh Hemmat
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): Xiao-Meng Liu, Xue-Qi Li, Qing-Lun Wang, Qian-Ying Liu, Yu-Zhang Tong, Xiao-Pu Jia, Chun Yang
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): Mansoor Akhtar, ShifaUllah Khan, Dong-Xia Zhu, Guo-Gang Shan, Zhong-Min Su
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
Publication date: Available online 26 May 2020Source: Inorganic Chemistry CommunicationsAuthor(s): Li Xiao, Jin-Meng Yang, Gao-Yuan Huang, Yue Zhao, Hai-Bin Zhu
Source: Inorganic Chemistry Communications - Category: Chemistry Source Type: research
More News: Biochemistry | Copper | Study